左炔诺孕酮宫内节育系统与去氧孕烯炔雌醇片治疗子宫内膜异位症疼痛疗效对比研究  

A comparative study on efficacy of Marvelon and Mirena in relieving pain caused by endometriosis

作　　者：杨新[1] 康佳丽[1] 丁红[2] 

机构地区：[1]广州市第一人民医院妇产科,广东广州510180 [2]广州市中山大学附属第二医院妇产科,广东广州510120

出　　处：《临床和实验医学杂志》2012年第19期1555-1557,共3页Journal of Clinical and Experimental Medicine

摘　　要：目的对比研究左炔诺孕酮宫内节育系统与去氧孕烯炔雌醇片治疗子宫内膜异位症疼痛的疗效。方法选取2008年7月至2011年7月收治的72例子宫内膜异位症患者,随机分为治疗组与对照组各36例,治疗组患者采用去氧孕烯炔雌醇片进行治疗,对照组患者采用左炔诺孕酮宫内节育系统进行治疗,对比分析两组患者的疼痛疗效。结果治疗组患者经治疗后有3例月经推迟1个月,2例闭经3个月。对照组患者2例月经推迟1.5个月,4例闭经2.8个月。经过治疗后,治疗组患者重度疼痛3例,中度疼痛6例,无痛27例,对照组患者重度疼痛2例,中度疼痛8例,无痛26例,两组无痛发生率差异无统计学意义(P>0.05)。结论左炔诺孕酮宫内节育系统与去氧孕烯炔雌醇片治疗子宫内膜异位症均可减轻患者疼痛感。Objective To compare the efficacy of Mirena and Marvelon in relieving pain caused by endometriosis.Methods Seventy two patients with endometriosis admitted in this hospital during July 2010 to February 2011 were randomly divided into trial group and control group,each with 36 patients,patients in trial group were treated with Marvelon,patients in control group were applied with Mirena for treatment,and the efficacy in remission of pain in patients of these two groups was compared.Results After treatment,patients with delayed menstruation for one month were seen in 3 cases,amenorrhea sustained for three months in 2 cases,and no significant change in remaining cases.Menstruation was delayed for 1.5 months in 2 cases of control group,amenorrhea was sustained for 2.8 months in 4 cases,and no significant change in remaining cases.After treatment,3 cases in trial group had severe pain,6 cases had moderate pain,and 27 cases relieved pain.In control group,2 cases had severe pain,8 cases had moderate pain and pain relieved in 26 cases.There was no statistically significant difference in relief of pain between these two groups（P0.05）.Conclusion The application of Mirena and Marvelon in treatment of endometriosis,both of them can relieve pain.

关 键 词：子宫内膜异位症 疼痛 左炔诺孕酮宫内节育系统 去氧孕烯炔雌醇片 

分 类 号：R711.71[医药卫生—妇产科学]