ICS联合沙丁胺醇雾化吸入对控制婴幼儿哮喘急性发作的临床观察  

Clinical observation of ICS combined with Salbutamol atomization inhalation to control infants' acute episoded asthma

作　　者：徐玲[1] 赵顺英[2] 

机构地区：[1]天津市大港油田总医院儿科,天津300280 [2]首都医科大学附属北京儿童医院儿科,北京100045

出　　处：《中国医药导报》2012年第28期78-79,共2页China Medical Herald

基　　金：国家自然科学基金(81070017)

摘　　要：目的观察研究布地奈德联合沙丁胺醇雾化吸入对控制婴幼儿哮喘急性发作的临床疗效。方法将160例哮喘急性发作的婴幼儿随机分为两组,每组80例。对照组给予常规抗感染、抗病毒、止咳化痰平喘以及吸氧治疗。研究组在常规治疗的基础上给予布地奈德与硫酸沙丁胺醇雾化吸入治疗。用药后观察比较两组患者喘憋、咳嗽等症状以及肺部湿啰音和肺部哮鸣音等体征消失情况,并比较两组治疗后的总有效率。结果研究组症状和体征消失时间明显短于对照组,总有效率高于对照组,差异均有高度统计意义(P<0.01)。结论吸入性糖皮质激素(ICS)联合沙丁胺醇雾化吸入能快速控制婴幼儿哮喘急性发作,不良反应少,治疗效果显著。Objective To observe and study clinical curative effects of Budesonide combined with Salbutamol atomization inhalation to control infants＇ acute episoded asthma. Methods 160 infants with acute episoded asthma were divided into two groups randomly, each group had 80 patients. The control group was given conventional fighting infection, fighting virus and cough eliminating phlegm to smooth wheezing and oxygen uptake as treatment; the study group was given Budes- onide combined with Salbutamol atomization inhalation on the basis of conventional treatment as treatment. The two groups＇ suppression and cough conditions, and the disappearing situation of lung moist rale and lung wheezing rale after taking the medicine were observed and compared, and the two groups＇ total effective rate was compared. Results The disappearing time of symptoms and signs in study group was obviously shorter than control group, and its total effective rate was higher than control group, the differences were all statistically significant （P 〈 0.01）. Conclusion ICS combined with Salbutamol atomization inhalation can control infants＇ acute episoded asthma rapidly, and it has few untoward effects, it has evident treatment effects.

关 键 词：布地奈德 沙丁胺醇 婴幼儿哮喘 临床疗效 

分 类 号：R725.6[医药卫生—儿科]