机构地区:[1]广州医学院第一附属医院微创中心泌尿外科广东省泌尿外科重点实验室,510230
出 处:《中华泌尿外科杂志》2012年第10期767-770,共4页Chinese Journal of Urology
摘 要:目的总结微通道经皮肾取石术(minimally invasive percutaneous nephrolithotomy,MPCNL)治疗上尿路结石的经验,探讨其临床适应证、疗效及安全性。方法1992年6月至2010年9月采用MPCNL治疗上尿路结石患者10452例,男6060例,女4392例。年龄7个月~93岁,平均(47.64-13.7)岁。结石大小为20~4080mm2,平均(777.44-740.3)mm2。回顾性分析手术操作技巧、手术时间、结石清除率、并发症、住院时间和部分结石成分分析结果。结果本组10452例共治疗肾脏10876个,其中左肾5493个(50.51%),右肾5383个(49.49%)。行MPCNL11801次,其中一期手术10102次(85.60%),二期手术1604次(13.59%),三期手术86次(0.73%),四期手术9次(0.08%)。共建立皮肾通道11830个,其中14F通道373个(3.15%),16F通道7867个(66.50%),18F通道3590个(30.35%)。经上盏、中盏和下盏入路分别为1207个(10.20%)、9174个(77.55%)和1449个(12.25%)。956个(8.79%)肾脏需多通道取石,其中双通道846个(7.78%),三通道85个(0.78%),四通道18个(0.17%)和五通道7个(0.06%)。使用气压弹道碎石器8563例(72.56%),钬激光碎石器2981例(25.26%),两者结合使用257例(2.18%)。术后需ESWL辅助治疗762例(7.29%)。手术时间10.0~240.0min,平均(101.3±44.2)min。MPCNL手术总结石清除率为89.9%,结合ESWL治疗后结石清除率为93.0%。住院时间2~72d,平均(13.2±6.4)d。出现明显并发症321例(3.07%),包括输血294例(2.81%),其中53例(0.51%)因出血严重行肾动脉超选择性栓塞治疗,脓毒症12例(0.11%),肾周脓肿2例(0.02%),胸膜损伤9例(0.09%),结肠损伤2例(0.02%),死亡2例(0.02%)。患者行结石成分分析4345例,主要成分为草酸�Objective To analyze the clinical indications, efficacy and safety of Chinese minimally invasive percutaneous nephrolithotomy (MPCNL) in treating upper urinary calculi based on our experience. Methods From June 1992 to September 2010, a total of 10,452 patients (6060 males and 4392 females) with a mean age of (47.6 ± 13.7) years (7 months- 93 years) received MPCNL in our center. The mean stone burden was (777.4 ± 740.3) mm2 (20 ± 4 080 mm2 ). The data of stone burden, operative tech-niques, operating time, stone-free rate, major complication, hospital stay and stone composition were inves- tigated. Results Of the 10 452 cases, 11 801 procedures were performed on 10 876 (5493 left and 5383 right) renal units, including 10 102 first stage procedures, 1604 secondary procedures, 86 third procedures and 9 fourth procedures. There were 11 830 tracts established, including 373 (3. 15% ) tracts of 14 F, 7867 (66.50%) tracts of 16 F and 3590 (30.35%) tracts of 18 F. There were 1207 (10.20%) , 9174 (77.55%) and 1449 (12.25%) punctures located in upper, middle and lower pole, respectively. 956 ( 8.79% ) renal units were managed with multiple tracts, which including 2 tracts in 846 (7.78%) units, 3 tracts in 85 (0.78%) units, 4 tracts in 18 (0.17%) units and 5 tracts in 7 (0.06%) units. Pneumatic lithotripsy was used in 8563 (72.56%) procedures, Holmium: YAG laser lithotripsy was used in 2981 (25.26%) procedures and Pneumatic lithotripsy + Holmium: YAG laser lithotripsy was used in 257 (2.18%) procedures. 762 (7.29%) cases needed ESWL to clean the stone after MPCNL. The average operating time was ( 101.3 ± 44.2) min ( 10 - 240 rain). The stone-free rate of MPCNL was 89.9% , which increased to 93% by adjunctive ESWL. And the mean hospital stay was (13.2 ± 6.4) days (2 -72 days). The major complications happened on 321 (3.07%) cases, including 294 (2.81% ) cases of blood transfu- sion, 12 (0.11% ) case
关 键 词:微通道经皮肾穿刺取石术 上尿路结石 回顾性分析
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