软硬酸碱规则与体内微量元素  

Hard and Soft Acid and Base Rule and Trace Elements in Body

作　　者：沈文英[1] 陈铭华[1] 

机构地区：[1]广东汕头大学医学院,广东汕头515031

出　　处：《广东微量元素科学》2000年第4期25-27,共3页Trace Elements Science

摘　　要：阐述了SHAB规则、分类、酸碱软硬度的定量标度和理论解释。根据SHAB规则把体内微量元素分为Lewis硬酸、软酸与交界酸和硬碱、软碱与交界碱。体内不同体液和器官含有丰富的软硬配体 ,与各类软硬酸 (金属离子 )结合成不同稳定性的配合物 。the hard and soft acid base rule,classification, scaling of hard and soft acid and the theory were explained According to the rule elements are classifed into Lewis hard-medial-soft acids(bases)in body .The compounds of trace elements (hard-medial-soft acids)and abundant ligand (hard-medial-soft bases)in differnt body fluid and apparatus make coordinative compounds of different stability ,playing on active biological effect in body

关 键 词：软硬酸碱 微量元素 生物活性 人体 SHAB规则 

分 类 号：Q581[生物学—生物化学]