Characterization of Nanostructures in Acellular Cementum of Human Tooth Roots  

作　　者：GAO Yong-bo LIU Ming-xia SUN Zhi-qiang ZHANG Kai DONG Feng-xia SUN Hong-chen YANG Bai 

机构地区：[1]Department of Oral Pathology,School of Stomatology,Jilin University,Changchun 130041,P.R.China [2]State Key Laboratory of Supramolecular Structure and Materials,College of Chemistry,Jilin University,Changchun 130012,P.R.China

出　　处：《Chemical Research in Chinese Universities》2012年第5期916-920,共5页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.30830108);the National Basic Research Program of China(No.2007CB936402)

摘　　要：Determining the microstructure in human cementum might help us design new kinds of replacement materials for the treatment of teeth injury and disease. The authors characterized the nanostructures in the cementum of health human teeth via scanning electronic microscopy（SEM）. It was found that the acellular cementum is mainly composed of two kinds of nanostructures―inorganic nanoparticles and organic nanofibers. And the inorganic nanoparticles show a tendency to arrange along the organic nanofibers. Based on the micro-molding in capillary strategy, the distribution of organic component in acellular cementum was copied with UV curable resin. After removing the inorganic nanoparticles by acid etching, many isolated spindle shape nanopores were left in polymer, which su- ggested that the inorganic nanoparticles should have been isolated by the organic component in cementum, and should be oval or nanosheet in shape. We hope the present work could provide reference for the biomimetic preparation of tissue engineering materials, and help us design new types of tooth implant.Determining the microstructure in human cementum might help us design new kinds of replacement materials for the treatment of teeth injury and disease. The authors characterized the nanostructures in the cementum of health human teeth via scanning electronic microscopy（SEM）. It was found that the acellular cementum is mainly composed of two kinds of nanostructures―inorganic nanoparticles and organic nanofibers. And the inorganic nanoparticles show a tendency to arrange along the organic nanofibers. Based on the micro-molding in capillary strategy, the distribution of organic component in acellular cementum was copied with UV curable resin. After removing the inorganic nanoparticles by acid etching, many isolated spindle shape nanopores were left in polymer, which su- ggested that the inorganic nanoparticles should have been isolated by the organic component in cementum, and should be oval or nanosheet in shape. We hope the present work could provide reference for the biomimetic preparation of tissue engineering materials, and help us design new types of tooth implant.

关 键 词：Acellular cementum NANOSTRUCTURE Root dentin 

分 类 号：TB383[一般工业技术—材料科学与工程] Q51[生物学—生物化学]