睡眠与2型糖尿病关系的病例对照研究  

Case-control study on the association of sleep and type 2 diabetes mellitus

作　　者：李志强[1] 吴东妮[2] 肖艳杰[1] 卢智泉[1] 

机构地区：[1]辽宁医学院公共卫生管理学院,锦州121001 [2]辽宁医学院护理学院

出　　处：《现代预防医学》2012年第19期5046-5047,5051,共3页Modern Preventive Medicine

摘　　要：目的探讨睡眠相关行为与2型糖尿病（T2DM）发病情况之间的关系,有效制定T2DM患者睡眠行为护理干预措施。方法科研设计采用1：1匹配的病例对照研究法;资料收集采用问卷调查法;资料处理分析采用t检验及多元条件Logistic回归模型分析法。结果病例组与对照组睡眠质量差异有统计学意义（t=10.15,P﹤0.05）。睡眠相关行为：午睡情况、晚睡情况、打鼾情况、入睡困难情况、夜间睡眠充足与否及睡眠质量等因素与T2DM发病存在关联,多元条件Logistic回归模型的OR值和OR95%CI分别为[（OR=6.70,95%CI：4.29-10.44）;（OR=7.57,95%CI：4.14-13.86）（OR=4.02,95%CI：2.56-6.31）;（OR=6.95,95%CI：3.52-13.71）;（OR=3.25,95%CI：1.99-5.30）;（OR=5.70,95%CI：3.65-8.87）]。结论睡眠相关行为与T2DM发病密切相关,晚睡、打鼾、入睡困难、夜间睡眠不足、睡眠质量差等因素可能为T2DM发病的危险因素,适当午睡可能是T2DM发病的保护性因素。OBJECTIVE To explore the association between sleep relative behaviors and the incidence of type 2 diabetes mellitus（T2DM）,and make the effect nursing measures for sleep behaviors of T2DM patients.METHODS Research design was taken case-control study for 1：1 pair-matching.Collected information with questionnaire investigation.Analyzed information by T test and multivariate conditional Logistic regression models.RESULTS There were significant differences of sleep quality between case group and control group（t = 10.15,P﹤ 0.05）.There was a association between sleep relative behaviors（nap,sleeping late,snoring,difficulty sleeping,not enough sleep at night and sleep quality） and T2DM.The multivariate conditional Logistic regression models showed odds ratios（ORs） and 95% confidence intervals were respectively [（OR = 6.70,95%CI：4.29-10.44）;（OR = 7.57,95%CI：4.14-13.86）;（OR = 4.02,95%CI：2.56-6.31）;（OR = 6.95,95%CI：3.5213.71）;（OR = 3.25,95%CI：1.99-5.30）;（OR = 5.70,95%CI：3.65-8.87）].CONCLUSION It should be noted that there is a closely relationship between sleep relative behaviors and T2DM in this study.Sleeping late,snoring,difficulty sleeping,not enough sleep at night and bad sleep quality may be danger to T2DM,but moderate nap may be benefit to T2DM.

关 键 词：睡眠 2型糖尿病 病例对照研究 

分 类 号：R587.1[医药卫生—内分泌]