妊娠高血压综合征孕妇血清胱抑素C水平变化病例对照研究  

Case-control study on serum cystatin C level in gravidas with pregnancy induced hypertension syndrome

作　　者：莫伟[1] 林还珠[2] 钟毓琼[1] 梁仪[1] 

机构地区：[1]广东医学院第二附属医院检验科,广东湛江524003 [2]广东医学院第二附属医院妇产科,广东湛江524003

出　　处：《检验医学与临床》2012年第19期2420-2421,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨妊娠高血压综合征孕妇血清胱抑素C水平变化及其临床价值。方法利用全自动生化仪测定56例健康妊娠晚期妇女和60例妊娠高血压综合征孕妇血清胱抑素C水平和其他肾功能指标。结果妊娠高血压综合征孕妇血清胱抑素C水平较健康晚期孕妇明显增高(P<0.01)。结论血清胱抑素C在重度妊高征孕妇中有明显变化,能反映妊高征者早期肾损害,同时反映病情发展。Objective To explore the changes and clinical value of cystatin C level in gravidas with pregnancy induced hypertension syndrome（PIH）.Methods The cystatin C level and other kidney function indexes were detected by the automatic biochemical analyzer in 56 healthy gravidas of late pregnancy and 60 gravidas with PIH.Results The cystatin C level in PIH gravidas was increased significantly compared to the healthy gravidas of late pregnancy（P0.01）.Conclusion The cystatin C level in severe PIV gravidas has significant change,which reflects the early renal damage in PIH as well as the progress of the disease condition.

关 键 词：妊娠 高血压 胱抑素 

分 类 号：R714.246[医药卫生—妇产科学]