γ-丁内酯乙氧基化合成内酯冠醚  

Synthesis of Lactonic Crown Ethers by Ethoxylation of γ-Butyrolactone

作　　者：胡学一[1] 方云[1] 赵权[1] 

机构地区：[1]江南大学食品胶体与生物技术教育部重点实验室化学与材料工程学院,江苏无锡214122

出　　处：《精细化工》2012年第10期952-954,964,共4页Fine Chemicals

基　　金：国家自然科学基金项目(21276113)~~

摘　　要：以Al-Mg基复合氧化物为催化剂,尝试采用环氧乙烷(EO)分子插入γ-丁内酯(GBL)的新反应合成内酯冠醚,用FTIR和ESI-MS对目标产物结构进行了确证。实验结果表明,LE-4催化剂的催化效果最佳;对反应温度和压力的优化实验进一步表明,当使用质量分数1%的LE-4催化剂,EO与GBL的摩尔比为5时,优化反应温度和体系压力分别为160℃和0.65 MPa,GBL转化率达到75.2%。Lactonic crown ethers were synthesized by a novel insertion reaction of ethylene oxides into γ-butyrolactone（GBL） catalyzed by Al-Mg composite oxide,and the molecular structures of the target products were confirmed by FTIR and ESI-MS.The process was optimized with respect to Al/Mg molar ratio of catalysts,reaction temperature and pressure.The conversion of GBL was 75.2% when the insertion reaction was catalyzed by 1% of LE-4 catalyst based on the target products and run in 5 times molar ratio of EO to GBL at 160 ℃ under 0.65 MPa.

关 键 词：内酯冠醚 乙氧基化 嵌入反应 Γ-丁内酯 环氧乙烷 催化技术 

分 类 号：O621.3[理学—有机化学]