高效液相色谱-串联质谱法测定润滑剂中的全氟有机化合物  

Simultaneous Determination of Ten Kinds of Perfluorinated Compounds in Lubricant Samples by High-performance Liquid Chromatography-Tandem Mass Spectrometry

作　　者：张代辉[1,2] 卢利军[1] 张勋[1] 牟峻[1] 周晓[1] 胡婷婷[1] 韩大川[1] 

机构地区：[1]吉林出入境检验检疫局,长春130062 [2]吉林大学生命科学学院,长春130023

出　　处：《应用化学》2012年第10期1163-1170,共8页Chinese Journal of Applied Chemistry

基　　金：国家质检总局课题(2007IK142);吉林检验检疫局科技课题(2009JK51)资助

摘　　要：建立了测定润滑剂中10种全氟有机化合物的高效液相色谱-串联质谱(HPLC-MS/MS)分析方法。不同类型的润滑剂样品经溶剂提取后,采用弱阴离子交换柱和石墨化碳柱净化,经C18色谱柱分离后进行HPLC-MS/MS多反应监测模式下的定性及定量分析。10种全氟有机化合物的方法检出限为0.001～0.005 mg/kg;在低、中、高的3个添加水平范围内的平均回收率在79.05%～106.26%;日内精密度均小于10%,日间精密度均小于20%。An analytical method based on high-performance liquid c has been developed for the determination of 10 perfluorinated compounds. Various lubricant samples were extracted with the solvent. Then the cartridge. Qualitative and quantitative extract was cleaned up by Oasis analyses were carded out for the WAX and Envi-carb solid phase analyte under the multiple reaction monitoring（MRM） mode after the chromatographic separation over Waters Xbridge C18（ 150 mm × 2. 1 3.5 μm）column. The limits of detection for 10 perfluorinated compounds were 0. 001 ～ 0. 005 mg/kg. mean recoveries at the three spiked levels were 79. 05% 10% and the inter-day precision less than 20%. ～ 106. 26%, with the intra-day precision less mm The than

关 键 词：高效液相色谱-串联质谱 润滑剂 全氟有机化合物 检测 

分 类 号：O656[理学—分析化学]