胸部多发伤出血性休克早期自体血回输救治的实验  

Early Autologous Blood Transfusion Treatment for the Hemorrhagic Shock of Thoracic Multiple Injuries

作　　者：李庆新[1] 孟辉[1] 郑军 洪波 张世范[1] 李乃斌[1] 高明[1] 杨俊峰 伍治强[1] 

机构地区：[1]兰州军区兰州总医院胸外科,兰州730050 [2]广州军区广州疗养院,广州510515

出　　处：《科技导报》2012年第27期61-64,共4页Science & Technology Review

基　　金：甘肃省科技支撑计划项目(1104FKCA106);甘肃卫生行业科研计划项目(GSWST09-19)

摘　　要：构建胸部创伤血气胸、失血性休克动物模型,应用集负压吸引、血液回收、抗凝过滤、自体输血、穿刺引流等多功能的一次性专利装置回收胸腔血,探讨自体血回输对重创失血休克血气胸救治效果。将普通级比格犬18只随机分为微创休克组(A组,n=6只)、重创血气胸失血性休克自体血回输组(B组,n=6只)、重创血气胸失血性休克非自体血回输组(C组,n=6只)。观察动物的存活率、生理指标、常规红细胞各项参数和血小板数量。结果表明,与对照组相比,实验组动物的存活率高,血液中红细胞等各项参数保持良好。运用自体血回收装置回输胸腔血对重创失血休克血气胸犬有明显的救治作用。Animal models for thoracic traumatic hemopneumothorax and hemorrhagic shock were constructed, and thoracic cavity blood were reclaimed by the disposable patented equipment, then the treatment effect of autologous blood transfusion was explored. Eighteen Beagles with common grade were randomly divided into three groups, which included mini-traumatic shock group （group A, n=6）, heavy traumatic shock and hemopneumothorax with autologous blood transfusion group （group B, n =6）, and heavy traumatic shock and hemopneumothorax with non-autologous blood transfusion group （group C, n=6）. Disposable patented equipments have the muhifunction including vacuum aspiration, blood reclaiming, anticoagulation filtering, autologous blood transfusion, paracentesis, and draining. Animal survival rate, red blood cell, white blood cell, hemoglobin, hematocrit, platelet, fibrinogen and coagulation function were observed. Comparing with the control group （group C）, the animals in experimental group （group A, B） have a higher survival rate and their parameters, such as red blood cell, keep better. Applying the autologous blood transfusion reclaiming patented equipment treatment to the beagles with heavy traumatic shock and hemopneumothorax has a conspicuous remedy effect.

关 键 词：自体血回输 失血性休克 血气胸 犬 

分 类 号：R655[医药卫生—外科学]