复方中药抗大肠杆菌内毒素作用研究  

Effect of Compound Traditional Chinese Medicine on Escherichia coli Endotoxin Action in Broilers

作　　者：史书军[1] 赵兴华[1] 杜健[1] 

机构地区：[1]河北农业大学动物医学院,河北保定071001

出　　处：《中国家禽》2012年第19期13-16,共4页China Poultry

基　　金：河北省科技支撑项目(09220415)

摘　　要：为研究中药复方治疗大肠杆菌病的机理,采用AA肉仔鸡作为试验动物,胸肌注射大肠杆菌内毒素,制作大肠杆菌内毒素致热病理模型,选择两个中药验方做体内和体外抗内毒素试验。结果表明,内毒素对肉仔鸡有显著致热效应(P<0.05),产生典型的双峰状发热曲线;所选中药复方制剂在体内和体外均有抗内毒素作用。AA broiler chickens were used as experimental animal to study the mechanism of compound traditional Chinese medicine against Escherichia coli endotoxin. Fever pathological model was established by injecting Escherichia coli endotoxin into breast muscle of chicken. Two compound traditional Chinese medicine were tested for the antiendotoxin effect in vitro and in vivo. The results showed that the endotoxin could significantly lead to fever in chicken （P〈O.05）with typical bimodal temperature curve. Both compound traditional Chinese medicine had the antiendotoxin effect in vivo and in vivo.

关 键 词：中药 大肠杆菌 内毒素 肉鸡 

分 类 号：S858.315.1[农业科学—临床兽医学]