生藤乙酸乙酯部位化学成分  

Chemical Constituents of Ethyl Acetate Extract Part of Stelmatocrypton khasianum

作　　者：莫小宇[1] 麦景标[2] 

机构地区：[1]中山市陈星海医院,广东中山528415 [2]广东三才石岐制药有限公司,广东中山528415

出　　处：《中国实验方剂学杂志》2012年第20期61-63,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:研究生藤中乙酸乙酯部位的化学成分。方法:采用硅胶柱色谱、MCI和Sephadex LH-20等分离手段对乙酸乙酯萃取部分进行分离纯化,通过波谱数据分析(1H-NMR、13C-NMR)进行结构鉴定。结果:从乙酸乙酯萃取部分分离5个化合物,分别鉴定为丁香脂素(Ⅰ),diasyringaresinol(Ⅱ),表丁香脂素(Ⅲ),justiciresinol(Ⅳ),threo-4',4″,7″,9″-tetrahydroxy-3,3',3″,5-tetramethoxy-4,8″-oxy-7,9'∶7',9-diepoxylignan(Ⅴ)。结论:5种化合物均为首次从该植物中分离得到。Objective： To study on chemical constituents of the ethyl acetate extract part of Stelmatocrypton khasianum. Method： Ethyl acetate extract part were isolated and pured by silica gel column chromatography, MCI and Sephadex LH-20, Their chemical structures were elucidated by spectral data analysis （IH-NMR and13C-NMR）. Result： Five compounds were isolated from the ethyl acetate extract part, they were identified as syringaresinol （ ] ）, diasyringaresinol （ Ⅱ ）, episyringaresinol （ HI ）, justiciresinol （ IV ）, threo- 4＇, 4 7, 9-tetrahydroxy-3, 3＇, 3, 5-tetramethoxy-4, 8-oxy-7,9＇： 7＇,9-diepoxylignan （ V ）. Conclusion ： Five kinds of compounds were isolated from S. khasianum for the first time.

关 键 词：萝藦科 生藤 乙酸乙酯部位 化学成分 

分 类 号：R284.1[医药卫生—中药学]