济南地区Ⅰ类切口手术围手术期抗菌药物使用调查  

Application of antibiotics in Jinan during perioperative period of Class Ⅰ incision surgery

作　　者：李国庆[1] 周文[2] 欧扬[2] 郭芳芳[2] 

机构地区：[1]山东大学药学院,山东济南250012 [2]山东大学齐鲁医院药剂科,山东济南250012

出　　处：《中华医院感染学杂志》2012年第19期4320-4322,共3页Chinese Journal of Nosocomiology

基　　金：山东省科学技术厅基金项目(2011RKE 27047)

摘　　要：目的了解济南地区医院Ⅰ类切口手术预防使用抗菌药物情况。方法对济南地区11所医院2010年1-12月出院的900例Ⅰ类切口手术病历进行回顾性调查分析。结果Ⅰ类切口手术患者抗菌药物使用率为98.00%,涉及12大类37个品种,其中应用最多的是一代头孢菌素;56.12%的Ⅰ类切口手术在术前30min～2h内给药;平均预防用药疗程为3.4d;联合用药的患者75例,占8.50%。结论济南地区Ⅰ类切口手术围手术期预防应用抗菌药物存在不合理性现象,需进一步规范临床医师抗菌药物使用行为,制定完善的围手术期预防用药管理措施。OBJECTIVE To investigate the prophylactic use of antibiotics for classⅠincision surgery in hospitals in Jinan.METHODS A total of 900 patients who received class Ⅰincision surgery and discharged from Jan to Dec 2010 were retrospectively analyzed.RESULTS The utilization rate of antibiotics took up 98.00%,involving 12 categories of antibiotics,37 varieties,the utilization rate of the first generation of cephalosporin was the highest among those antibiotics;56.12% of patients took antimicrobial agents 30 min-2 h before the surgery;the average course of prophylactic use of antibiotics was 3.4 days,there were 75（8.50%） patients who used combination use of antibiotics.CONCLUSION There exists irrational phenomenon in the preoperative preventive application of antibiotics for classⅠincision surgery,it is necessary to further standardize the clinical application of antibiotics and develop complete measures for prophylactic use of antibiotics.

关 键 词：Ⅰ类切口手术 围手术期 抗菌药物 济南地区 

分 类 号：R978.1[医药卫生—药品]