四城市成人血液中主要重金属含量分析  

Concentration and comparison studies of main heavy metals in adult blood in four cities

作　　者：闫赖赖[1] 陈曦[2] 王京宇[1] 诸洪达[3] 解清[1] 武权[3] 欧阳荔[1] 

机构地区：[1]北京大学公共卫生学院中心实验室,北京100191 [2]中国疾病预防控制中心环境与健康相关产品安全所 [3]中国医学科学院中国协和医科大学放射医学研究所

出　　处：《卫生研究》2012年第5期840-843,共4页Journal of Hygiene Research

基　　金：新教师科研启动基金(No.BMU20090501-123);国家自然科学基金(No.30972434)

摘　　要：目的比较四城市成人血液中5种主要重金属的浓度差异及来源。方法采用电感耦合等离子体质谱仪(ICP-MS)、双道原子荧光光度计(AFS)对我国膳食类型不同的4城市(太原、天津、成都、镇江)的健康成年男性血液中五种重金属元素含量进行测定及比较。结果血铅、血镉浓度:成都、太原>天津、镇江;血铜浓度:太原>镇江;血汞浓度:太原>镇江、天津、成都;血砷浓度:镇江>太原>天津、成都。整体来看,有"东西差异"现象,即成都、太原重金属元素整体浓度高于天津、镇江;血液内部重金属元素间相关有统计学意义。结果血液重金属在城市间的差异可能与生活环境、饮食习惯的不同有关;重金属元素间的相关提示应综合其它相关元素来研究重金属的毒害作用。Objective To study the concentration difference and source of five kinds of heavy metals in the adult blood in four cities. Method Concentrations of five kinds of heavy metals in the healthy man blood were determined and compared by ICP-MS or AFS, which came from four different kinds of dietary cities, those are Taiyuan, Tianjin, Chengdu, Zhenjiang. Results Contents of blood Pb and Cd in Chengdu , Taiyuan were higher thanjian Jin, Zhenjiang, Taiyuan were higher than Zhenjiang in blood Cu and higher than other cities in blood Hg, however, contents of blood As in Zhenjiang were higher than other three cities. In the whole, there was a phenomenon, that was, contents of five heavy metals in Chengdu, Tai Yuan were higher than Tianjin, Zhenjiang. Correlation of heavy metals in the blood were of statistical significance. Conclusion The difference of heavy metals in the blood related to different living surrounding and dietary habit. The correlation result suggested we should study the poisoning effect integrating other relative element.

关 键 词：血液重金属 电感耦合等离子体质谱仪浓度 

分 类 号：R994.6[医药卫生—毒理学] R155.33[医药卫生—药学]