尿中TXB_2和6-Keto-PGF_(1α)放射免疫分析的临床应用  

The clinical application of radioimmunoassay of TXB_2 and 6-keto-PGF_(1a) in the urine

作　　者：杨梅芳[1] 张敬礼[2] 赵淑静 巩维如[1] 赵云涛[4] 叶剑雄[4] 赵玉海[5] 马三元[1] 董晓军[1] 李振甲[1] 

机构地区：[1]中国人民解放军军医进修学院生化研究室 [2]解放军105医院 [3]解放军268医院 [4]海军总医院 [5]吉林省干部疗养院

出　　处：《军医进修学院学报》1990年第1期73-75,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：本文初步观察10组病例应用放射免疫分析尿中TXB_2和6-Keto-PGF_(1α)浓度变化,在临床疾病中的意义。结果表明,正常人对照组测定浓度TXB_2为191.9±23.6pg/min,6-keto—PGF_(1α)为为511.0±82.6pg/min(X±SEn=14)。尿毒症患者尿中TXB_2为45.5±8.5pg/min,6-Keto-PGF_(1α)39.8±16.1pg/min(X±SEn=12)。与对照组统计学分析比较相差非常显著P<0.01。其余各组尿中TXB_2测值较对照组有不同幅度升高,统计学分析相差显著P<0.05或相差非常显著P<0.01。6-Keto-PGF_(1α)测值随病情程度或不同疾病其变化不同。In this paper, Preliminary study changes significance of radioimmunoassay of urinary TXB_2 and 6-keto-PGF_(1a) in the 10 groups case. Result expression, The concetrotion assay value of the normal control of TXB_2 and 6-keto-PGF_(1a) were 191. 9±23.6pg/min and 511.0±82.6 pg/min (X±SE n = 14) respectively. The assay value of the urinemiapatients of TXB_2 and6-keto-PGF_(1a) wree 45.5±8.5 pg/min and 39.8±16.1 pg/min (X±SEn=12) respectively. In comparison were to control group p<0.01.In other patient group, The value of TXB_2 in the urinary Were all higher in varying degrees thar the normal control. Statistical study (p<0.05 or p<0.01), On the other hand, Thevalue of 6-keto-PGF_(1a) changes difference according to serious extent or variant disease.

关 键 词：血栓素A2 放射免疫测定 尿 6-KETO-PGF1Α 

分 类 号：R446.122[医药卫生—诊断学]