低氘水抗肿瘤作用的研究进展  

Research progress of the inhibitory effect of deuterium-depleted water on cancers

作　　者：王宏强[1,2] 刘聪[2] 方唯意[3] 杨慧龄[1,2] 

机构地区：[1]广东医学院中美肿瘤研究所,广东东莞523808 [2]南华大学药物药理研究所,湖南衡阳421001 [3]南方医科大学肿瘤研究所,广东广州510515

出　　处：《南方医科大学学报》2012年第10期1454-1456,1460,共4页Journal of Southern Medical University

基　　金：国家自然科学基金(30971438;81272334)~~

摘　　要：目的 氘是致癌的重要诱发因素之一，通过采用先进的制造技术去除天然水中的氘，降低氘含量可制得贫氘水，又称低氘水、超轻水或无氘水。有研究表明，水中氘浓度体积分数减少65%能够抑制肿瘤生长，国外临床实验证实服用低氘水（10-20 ppm）的肿瘤患者能使肿瘤停止生长，显著提高患者的生存时间和生活质量。目前，抗癌化疗药物种类繁多，但都存在一定局限性，而低氘水使用方便，没有毒副作用。基于低氘水的显著优势，本文主要对低氘水的抗癌作用的研究进展作一综述。Objective Deuterium is an important predisposing factor for cancer.Deuterium-depleted Water,also known as low deuterium water,ultra-light water or no deuterium water,can be obtained by removing deuterium from natural water.Studies have shown that water with a low deuterium concentration（65% percent of volume） can inhibit cancer growth.Clinical trials demonstrated that drinking DDW（10-20 ppm） caused growth arrest of malignant cells in cancer patients and significantly prolonged the patient survival with also improved quality of life.A wide range of anti-cancer drugs in current use are associated with severe adverse effects,while deuterium-depleted water appears to have virtually no pharmacological side effects and is convenient to administer.The authors review the advances in the researches of anti-cancer effects and the underlying mechanisms of deuterium-depleted water.

关 键 词：氘 癌症 低氘水 抗癌 

分 类 号：R96[医药卫生—药理学]