匹多莫德治疗小儿咳嗽变异性哮喘的临床研究  

Clinical study of pidotimod in the treatment of children with cough variant asthma

作　　者：严小光[1] 毕云红 

机构地区：[1]吉林省人民医院儿科,吉林长春130021 [2]吉林省伊通满族自治县第三人民医院儿科,吉林伊通130700

出　　处：《吉林医学》2012年第28期6071-6072,共2页Jilin Medical Journal

摘　　要：目的:研究匹多莫德在治疗小儿咳嗽变异性哮喘中的有效性及安全性。方法:选择小儿咳嗽变异性哮喘患儿60例,随机分为观察组和对照组各30例,两组患儿均给予糖皮质激素吸入及孟鲁司特片口服治疗,观察组加用匹多莫德口服,观察两组患儿的临床疗效、不良反应,并随访1年内复发情况。结果:观察组总有效率96.6%,高于对照组总有效率(86.7%),差异有统计学意义(P﹤0.05);观察组1年内复发率(10%)低于对照组复发率(26.6%),差异有统计学意义(P﹤0.05);两组患儿均未见明显不良反应。结论:匹多莫德对小儿咳嗽变异性哮喘的治疗和病情复发控制均有积极意义,且无临床不耐受性。Objective To study the effect and security of pidotimod in the treatment of children with cough variant asthma.Method 60 cases of children with cough variant asthma in children were randomly divided into observation group and control group and 30 cases in each group,two groups of children were treated with inhaled corticosteroids and montelukast tablet treatment,observation group were added with pidotimod orally,observed the clinical efficacy of two groups of children with adverse reactions and 1 year follow-up recurrence.Results The total efficiency of observation group was 96.6% and it was higher than the control group of 86.7%,had a significant difference（P0.05）;1 year recurrence rate of the observation group was 10%and it was lower than the control group of 26.6%,had a significant difference（P0.05）;The children of two groups were no obvious adverse reactions.Conclusion Pidotimod in the treatment of children with cough variant asthma have positive significance and no clinical intolerance.

关 键 词：匹多莫德 咳嗽变异性哮喘 小儿 

分 类 号：R725.6[医药卫生—儿科]