阴道部分闭合术疗效及生活质量评价  

Efficacy of Le Fort operation and its impact on patients＇ quality of life

作　　者：苗娅莉[1] 蒋励[1] 谢敏[1] 王建六[1] 

机构地区：[1]100044,北京大学人民医院妇科

出　　处：《中华医学杂志》2012年第37期2645-2648,共4页National Medical Journal of China

摘　　要：目的了解阴道部分闭合术（Le Fort operation）的疗效及患者术前术后生活质量情况，评价阴道闭合术的客观和主观疗效。方法回顾性分析2005年10月至2010年3月北京大学人民医院因盆腔器官脱垂而接受阴道部分闭合术患者48例，术后定期随访，随访包括妇科检查及问卷调查。评价患者症状及生活质量的问卷包括：盆底功能障碍问卷简要版-20（PFDI-20）及盆底功能影响问卷简要版-7（PFIQ-7）。结果40例患者均有完整随访资料，平均随访22．3（12-42）个月，复发1例，新发压力性尿失禁6例，新发肠道症状2例。术后PFDI-20、PFIQ-7总分及泌尿生殖道症状调查表（UDI-6）、盆腔脏器脱垂症状调查表（POPDI-6）得分均较术前显著降低（P〈0．05）。结论阴道部分闭合术能够显著改善盆腔器官脱垂症状、下尿路症状及生活质量，对肠道症状改善尚不明确。Objective To evaluate the objective and subjective effiacies of Le Fort operation and its impact on patients＇ quality of life before and after operation. Methods A total of 48 patients with pelvic organ prolapse undergoing Le Fort operation from October 2005 to May 2010 were recruited. Their clinical data were retrospectively analyzed and regular follow-ups of pelvic examinations and questionnaires conducted. The questionnaires included pelvic floor distress inventory-short form 20 （PFDI-20） and pelvic floor distress impact questionnaire-short form 7 （ PFIQ-7 ）. Results Forty patients had complete follow-up data. Their mean follow-up period was 22. 3 months （ range： 12 - 42 ）. Among them, there were recurrence （ n = 1 ）, new-onset stress uinary incontinence symptoms （ n = 6 ） and new-onset colorectal-anal symptoms （n =2）. The postoperative scores of PFDI-20, PFIQ-7, UDI-6 and POPDI-6 decreased markedly （P 〈 0. 05）. Conclusion Le Fort operation can significantly improve patients＇ quality of life and subjective prolapse symptoms and lower urinary tract. However its improvement of colorectal-anal symptoms remains to be defined.

关 键 词：盆腔脏器脱垂 阴道 外科手术 疗效比较研究 生活质量 

分 类 号：R713[医药卫生—妇产科学]