喜炎平注射液治疗流行性乙型脑炎临床观察  

Clinical Observation of Xiyanping Injection and Its Effects on Epidemic Encephalitis-B

作　　者：凃晋文[1,2] 董梦久[1] 刘志勇[2] 牟艳杰[2] 

机构地区：[1]湖北省中医院脑科,湖北武汉430061 [2]湖北中医药大学临床医学院,湖北武汉430065

出　　处：《南京中医药大学学报》2012年第5期434-436,共3页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：国家中医药管理局传染病防治行业专项(200907001-8)

摘　　要：目的探索治疗流行性乙型脑炎(乙脑)更有效的方法。方法 172例流行性乙型脑炎患者,其中随机研究组90例,队列研究组82例。随机分为2组,治疗组86例乙脑患者在与对照组86例相同的综合治疗及护理基础上用喜炎平注射液治疗,其中小儿10～15mg/(kg.d)加入5%葡萄糖注射液或氯化钠注射液100～200mL稀释后静脉滴注,滴速为每分钟20～30滴,日1次;成人1日250～500mg,日1次,加入5%葡萄糖注射液或氯化钠注射液200～250mL稀释后静脉滴注,连用15d。结果随机研究治疗组在降温(5.12±1.23)d、平均昏迷时间(6.41±1.08)d、平均缓解抽搐时间(3.24±1.26)d、平均住院天数(23.00±2.03)d;队列研究治疗组在降温(5.50±1.30)d、平均昏迷时间(5.84±1.03)d、平均缓解抽搐时间(2.23±1.19)d、平均住院天数(22.00±2.19)d均比对照组短,且恶化和后遗症较少,治愈率高,疗效明显优于对照组(P<0.05!。结论喜炎平注射液是目前治疗乙脑的有效方法之一,值得推广应用。OBJECTIVE To explore more effective ways of treating epidemic encephalitis-B.METHODS 172 cases（90 cases in random research group and 82 cases in alignment research group） were divided into 86 in treatment group and 86 in control group.Patients in the treatment group were given Xiyanping injection（children：i.g.10~15 mg/（kg·d） with 100~200 mL 5% glucose injection or NaCl injection,20~30 drip per min once a day;adults： i.g.250~500 mg per day with 200~250 mL 5% glucose injection or NaCl injection for 15d） together with comprehensive treatment and basic nursing as the control group.RESULTS In the random research treatment group,the decreased temperature,average coma time,average spasm relieving time,average hospitalization time was（5.12±1.23） d,（6.41±1.08） d,（3.24±1.26） d and（23±2.03） d respectively,which was significantly short than the control group;in the alignment research treatment group,the decreased temperature,average coma time,average spasm relieving time,average hospitalization time was（5.50±1.30） d,（5.84±1.03） d,（2.23±1.19） d and（22±2.19） d,which was significantly short than the control group with less deprivation and sequela,higher healing rate.Time for decreasing body temperature,relieving spasm,conscious recovery and average hospitalization was less than the control group（P0.05）.CONCLUSION Xiyanping injection is an effective way to treat epidemic encephalitis-B at present,which is worth further application promotion.

关 键 词：流行性乙型脑炎 喜炎平注射液 临床观察 

分 类 号：R254.3[医药卫生—中医内科学]