无偿献血者筛查项目——丙氨酸氨基转移酶  

THE ALT-Screening Project of Gratis Blood Donors

作　　者：魏淑梅[1] 王洪[1] 张红梅[1] 王志梅[1] 孙国栋[1] 王立芹[2] 

机构地区：[1]邯郸市中心血站,河北邯郸056001 [2]河北医科大学公共卫生学院,石家庄050017

出　　处：《医学综述》2012年第18期3037-3040,共4页Medical Recapitulate

摘　　要：丙氨酸氨基转移酶(ALT)是病毒性肝炎的非特异性指标,病理因素和非病理因素均可使ALT值异常升高,ALT检测结果超标是国内采供血机构血液报废的主要原因。目前GB-18467-2001《献血者健康检查要求》规定的ALT上限是否适合国内新时期献血人群值得探讨,开展对ALT参考值的调查,分析ALT不合格的影响因素,对于ALT标准的修订、血源的保护以及指导血液机构采供血工作均具有重要意义。Alanine aminotransferase（ALT）is nonspecific index of viral hepatitis.Both pathological factors and physiological factors can cause abnormal ALT value increase.Out-of-standard ALT test results is the main cause of blood rejection for blood institutions in China.At present,whether the GB-18467-2001 provisions to blood donors for ALT screening as upper limit of ALT is suitable for the new period in China needs to be discussed.Research on ALT reference value and analysis on the influence factors of unqualified ALT all have great significance for the revision of ALT standard,the protection of blood source and guiding the work in blood institutions.

关 键 词：丙氨酸氨基转移酶 献血者 参考值 影响因素 

分 类 号：R446[医药卫生—诊断学]