麻醉药物与免疫反应的研究进展  

Research Progress of Anesthetics and Immune Response

作　　者：郭航[1] 张生锁[1] 潘宁玲[1] 

机构地区：[1]北京军区总医院麻醉科,北京100700

出　　处：《医学综述》2012年第18期3050-3053,共4页Medical Recapitulate

摘　　要：麻醉药物广泛应用于临床麻醉和患者的镇静及镇痛,其对机体的免疫系统具有直接或间接的影响。接受手术治疗的重症患者免疫功能通常处于失调或被破坏的状态,任何操作和应激都有可能进一步影响其免疫功能和预后。有研究结果表明,麻醉药物的免疫抑制作用可能有助于减轻患者的全身炎性反应,并且与肿瘤患者术后的病死率和复发率密切相关。因此,深入研究麻醉药物对免疫功能的影响对于围术期患者用药具有重要意义。Being prevalent in clinical anesthesia and sedative and analgesic use in patients,anesthetics have direct or indirect effects on immune response.The immune system of many critically ill patients are unbalanced or impaired,any little manipulation or stimulation may further affect their immune functions and prognosis.Current studies show that anesthetics may reduce the systemic inflammatory responses of patients and have a close relation with the mortality and recurrence in cancer patients.Therefore,further study of the effects of anesthetics on immune response is important for medication of the perioperative patients.

关 键 词：麻醉药物 免疫反应 肿瘤患者 免疫系统 

分 类 号：R971[医药卫生—药品]