红花和甘草黄酮的协同抗炎镇痛作用分析  被引量:11

Analysis of Synergistic Effect on Anti-inflammation and Analgesia of Red Flower and Licoflavone

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作  者:安晓晶[1] 王晓娜[1] 马成俊[2] 李刚[2] 王振华[1] 

机构地区:[1]石河子大学药学院新疆特种植物药资源教育部重点实验室,新疆石河子832002 [2]烟台大学海洋学院

出  处:《西部中医药》2012年第10期20-22,共3页Western Journal of Traditional Chinese Medicine

摘  要:通过醋酸致小鼠扭体、血管通透性、血栓形成实验考查红花和甘草黄酮的抗炎镇痛作用。发现单独应用红花或甘草,无明显抗炎镇痛活性,两者联合应用抗炎镇痛活性明显增强,表明两种联用,具有明显的协同作用,且两者按1∶1比例组方时活性最强。此外还初步研究了其优选组方制备成凝胶剂的抗炎镇痛活性。Anti-inflammation and analgesia of red flower and licoflavone was investigated through the experiments of body torsion induced by acetic acid, vasopermeability and thrombosis. It was found that application of red flower or licorice didn't show remarkable anti-inflammatory and analgesic function separately, application of both suggested notable anti-inflammatory and analgesic function, which demonstrated that united application showed significant synergistic effect, and when the ratio was 1:1, they had the strongest active. In addition, anti-inflammatory and analgesic effects of optimized formula were initially studied.

关 键 词:静脉炎 红花 甘草黄酮 

分 类 号:R28[医药卫生—中药学]

 

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