庚型肝炎病毒母婴传播的研究  

Study on the mother-to-infant transmission of hepatitis G virus.

作　　者：覃锦耀[1] 陆继培[2] 韦小敏[2] 李春灵[2] 何飞屏[1] 

机构地区：[1]广西医科大学第一附属医院,南宁530021 [2]广西医科大学公共卫生学院

出　　处：《广西预防医学》2000年第3期139-141,共3页Guangxi Journal of Preventive Medicine

摘　　要：目的了解庚型肝炎病毒(HGV)在普通孕产妇群体中的感染情况和母婴传播的情况。方法血中抗 -HGV采用ELISA法检测 ,HGVRNA采用RT -PCR法检测。结果在848名普通孕产妇中 ,抗 -HGV阳性者46名 ,阳性率为5.42 % ;在46名抗 -HGV阳性孕产妇中 ,HGVRNA阳性者5名 ,符合率为10.86 % ,在5名HGVRNA阳性孕产妇中 ,其新生儿HGVRNA阳性者2名 ,传播率为40 %。结论HGV在普通孕产妇中的感染率为5.42 % ,其母婴传播机率高达40 %。Objective To explore the situation of HGV infection in normal pregnant and puerperal women and the possibility of HGV transmission by mother to infant route.Methods Antibodies against hepatitis G virus (anti_HGV) were detected by enzyme_linked immunosorbent assay(ELISA)and HGVRNA were detected by RT_PCR technique in women and infants sera.Results 46 positive sera of anti_HGV were found in 848 normal pregnant and puerperal women sera with a positive rate of 5.42%;5 positive sera of HGVRNA were found in 46 anti_HGV positive sera with a coincident rate of 10.86%;2 newborn's umbilical cord positive sera of HGVRNA were found in 5 newborn's umbilical cord sera from their mothers with positive HGV RNA,with a HGV transmission rate of 40%.Conclusion The infection rate of HGV was 5.42% in normal pregnant and puerperal women and the HGV transmission rate by mother_to_infants route reached 40%. [

关 键 词：庚型肝炎病毒 传播 母婴 流行病学 

分 类 号：R512.630.1[医药卫生—内科学]