精浆中SIgA,IgG含量检测及其临床意义  

Content Examination of SIgA and IgG in Sperm and Its Clinical Value

作　　者：闫家阁[1] 张纪云[1] 

机构地区：[1]临沂医学专科学校,山东临沂276002

出　　处：《潍坊医学院学报》2000年第2期108-109,共2页Acta Academiae Medicinae Weifang

摘　　要：目的　探讨精浆中分泌型免疫球蛋白 A(secretory immunoglobulin A,SIg A)、免疫球蛋白 G(Ig G)在男性生育和不育中的作用。方法　应用放射免疫分析 (RIA)方法对 2 2例正常生育者和1 2 5例不育症患者精浆中的 SIg A,Ig G进行了检测。结果　不育症患者各组精浆中 SIg A和 Ig G含量均明显低于正常生育者 (P<0 .0 5或 P<0 .0 1 ) ,尤以无精子症组和精子数 <2 0× 1 0 9/ L的少精子症组最为显著。结论　检测精浆中的 SIg A和 Ig G含量 ,对于观察男性的生育状态 ,判断不育症患者的病理变化机制 。Objective To explore the functions of secretory IgA (SIgA) and Immunoglobulin G (IgG) in sperm in cases of normal fertility and infertility.Method The contens of SIgA and IgA in sperm was examed through radioimmunoassay (RIA) in 22 cases of normal fertility and 125 cases of infertility.Result The contents SIgA and IgG in sperm of patients with infertility was found markedly lower than that in cases of normal fertility (P<0.05 or P<0.01).Significant difference existed in cases of azoospermia and spermcrasia and cases of normal fertility.Conclusion Content examination of SIgA and IgG can help to observe the male reproduction state,to determine the mechanism of pathological changes in cases of infertility and to choose proper clinical treatment. [

关 键 词：精浆 分泌型免疫球蛋白A 免疫球蛋白G 不育症 

分 类 号：R698.2[医药卫生—泌尿科学]