Amberlyst-15 in PEG：A novel catalytic system for the facile and efficient one-pot synthesis of benzothiazolo-[2,3-b]-quinazolinone derivatives  

作　　者：MAZAAHIR Kidwai RITIKA Chauhan DIVYA Bhatnagar 

机构地区：[1]Green Chemistry Research Laboratory,Department of Chemistry,University of Delhi

出　　处：《Science China Chemistry》2012年第10期2154-2160,共7页中国科学（化学英文版）

摘　　要：A simple and convenient approach for the synthesis of tetraheterocyclic benzothiazolo-[2,3-b]-quinazolin-1-ones has been developed utilizing the MCR methodology, which involves the condensation of 2-aminobenzothiazole, cyclic-diketones and various aldehydes using Amberlyst-15 in PEG 400 as an environmentally benign and reusable catalyst system. Environmental benignity, recyclability, cost-effectiveness, easy workup and excellent yields are the major attributes of this one-pot procedure.A simple and convenient approach for the synthesis of tetraheterocyclic benzothiazolo-[2,3-b]-quinazolin-1-ones has been developed utilizing the MCR methodology, which involves the condensation of 2-aminobenzothiazole, cyclic-diketones and various aldehydes using Amberlyst-15 in PEG 400 as an environmentally benign and reusable catalyst system. Environmental benignity, recyclability, cost-effectiveness, easy workup and excellent yields are the major attributes of this one-pot procedure.

关 键 词：Amberlyst-15 benzothiazolo-[2 3-b]-quinazolinones multi-component reaction REUSABILITY PEG （polyethylene glycol） green chemistry 

分 类 号：O626[理学—有机化学]