经导管溶栓治疗在急性下肢动脉缺血治疗中的作用研究  

Effect of Catheter Thrombolytic Therapy to Acute Lower Limb Ischemia

作　　者：史伟浩[1] 何勍[1] 朱磊[1] 谭晋韵[1] 王劲松[2] 余波[1] 

机构地区：[1]复旦大学附属华山医院外科,上海市200040 [2]中山大学附属第一医院血管外科

出　　处：《中国全科医学》2012年第28期3249-3252,共4页Chinese General Practice

基　　金：国家自然科学基金(81070257)

摘　　要：目的探讨采用经导管溶栓治疗急性下肢动脉缺血的疗效和安全性。方法收集2009年1月—2012年3月就诊于华山医院的急性下肢动脉缺血行导管溶栓治疗的病例共26例,采用尿激酶溶栓,观察溶栓治疗的效果和并发症。结果 23例患者通过溶栓治疗动脉得以成功开通,2例患者行膝下截肢,1例患者最终行切开取栓。本组无围术期死亡病例,无导管溶栓直接相关的并发症,术后出现急性肾功能不全1例,心功能不全1例,均经内科治疗1周缓解。结论导管溶栓是治疗急性下肢动脉缺血的较为安全、有效的方法。Objective To investigate the efficacy and safety of transcatheter thrombolytic therapy in treatment of patients with acute lower limb ischemia. Methods Totally 26 patients with acute lower extremity arterial ischemia in our hospital From January 2009 to March 2012 who underwent line catheter thrombolytic therapy were collected. Urokinase thrombolysis was used to observe the effects and complications of the thromholytic therapy. Results There were 23 patients whose arteries had been re -canalized, 2 patients who underwent below knee amputation, and one patient ultimately underwent open embolectomy. No perioperative death was found in the patients, no catheter thrombolysis directly -related complication was found. And there was one patient who had acute renal failure and one who had cardiac insufficiency; however both were remitted by one week medical treatment. Conclusion Catheter - directed thrombolysis is a relatively safe and effective treatment for acute lower limb ischemia.

关 键 词：导管溶栓 下肢 动脉 缺血 治疗结果 

分 类 号：R658.3[医药卫生—外科学]