基于放射介入联合中药方法对输卵管妊娠患者血清β-HCG和病灶大小的影响  

Effect of Radiation Intervention Combined with Traditional Chinese Medicine Therapeutic Methods on β-HCG Level in Serum and Lesion Size in Tubal Pregnancy Patients

作　　者：冯桂松 

机构地区：[1]山东省高密市人民医院,山东高密261500

出　　处：《中国实验方剂学杂志》2012年第21期297-299,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:观察放射介入联合中药治疗输卵管妊娠的临床疗效及安全性。方法:将62例输卵管妊娠患者随机分为对照组和研究组,对照组采用放射介入输卵管插管持续灌注氨甲蝶呤(MTX)治疗,研究组在此基础上辅以中药异位妊娠方治疗,疗程2周。观察治疗前后两组疗效、临床症状体征消失时间、血β-绒毛膜促性腺激素(β-HCG)水平、包块大小的变化以及副反应发生情况。结果:两组治疗2周后,研究组治愈率90.3%,对照组治愈率74.2%,具有显著性差异(P<0.05)。研究组相关症状消失时间、血β-HCG水平恢复及转阴时间、包块缩小率等相关疗效指标均优于对照组,差异显著,并且研究组副反应发生率明显低于对照组。结论:放射介入输卵管插管持续灌注MTX辅助中药治疗输卵管妊娠疗效显著,可明显缩短治愈时间,且毒副作用小,值得临床推广应用。Objective： To observe the clinical efficacy and safety of radiation intervention combined with traditional Chinese medicine （TCM） in treatment of tubal pregnancy. Method： Sixty-two patients were randomly divided the into control group and research group. The control group was treated with radiation intervention to fallopian tube combined with continuously methotrexate （MTX） infusion. The research group was treated with ectopic pregnancy prescription for 2 weeks based on above mentioned method. The disappeared time of clinical symptoms, theβ-human chorionic gonadotropin （/3-HCG） level in serum, the changes of lesion size, and the occurrence of side effect before and after the therapeutics were observed. Result： After 2 weeks, the cure rate for research group was 90.3% , and the control group was 74.2% , and there was significant difference （P 〈 0.05）. The relative efficacy indexes of research group （.such as the disappeared time of clinical symptoms, the recovered time ofβ-HCG level in serum, and the narrow rate of lesion size） were better than control group. Conclusion： The radiation intervention combined with TCM indicates significantly therapeutic efficacy, it can obviously reduce the cure time and side effects, and there was certain clinical application value.

关 键 词：放射介入 氨甲蝶呤 异位妊娠方 输卵管妊娠 

分 类 号：R287[医药卫生—中药学]