实时三维超声心动图与二维斑点追踪成像技术共同评价冠心病患者左心室收缩功能与同步性及二者相关性初探  

Evaluation of Left Ventricular Systolic Function and Synchrony in Patients with Coronary Heart Disease Using Real-time Three-dimensional Echocardiography and Two-dimensional Speckle Tracking Imaging

作　　者：刘利[1] 王志刚[1] 任建丽[2] 容跃[1] 

机构地区：[1]重庆医科大学超声影像学研究所,重庆市400010 [2]重庆医科大学附属第二医院超声科

出　　处：《中国超声医学杂志》2012年第10期917-920,共4页Chinese Journal of Ultrasound in Medicine

基　　金：国家自然科学基金面上项目(No.81071158);青年科学基金(No.81000621);教育部高校博土点基金新教师类(No.20105503120008)资助

摘　　要：目的探讨实时三维超声心动同(RT-3DE)与二维斑点追踪成像技术(2D-STI)评价冠心病患者左心室收缩功能与同步性的应用价值,并初步研究2种技术的相关性。方法 55例患者根据冠状动脉造影结果分3组,对照组25例,分别进行2D-STI和RT-3DE。分析心肌收缩期峰值纵向应变(LS)、径向应变(RS)和圆周应变(CS),并测量左心室短轴水平心肌节段收缩期达峰值径向应变的时间(TRS)及前间壁和后壁TRS的差值(TAS-POST);分析17节段时间容积曲线,获得左室舒张末期容积(EDV)、收缩末期容积(ESV)、射血分数(EF)及左心室16节段达到最小收缩容积时间差的标准差校正值(Tmsv-16-SD%),并对Tmsv-16-SD%与TAS-POST行相关性分析。结果病例组各参数与对照组对应参数比较,差异均有统计学意义(P<0.05),病例组间比较,多支病变组EDV、ESV及TAS-POST高于LCA组与RCA组(P<0.05),多支病变组、LCA组LS与Tmsv-16-SD%与RCA组有明显差异。Tmsv-16-SD%与TAS-POST呈显著正相关(r=0.794,P<0.01)。结论 RT-3DE与2D-STI均能较好地评价不同冠状动脉狭窄的冠心病患者左心室的收缩功能与同步性变化情况,并且2种技术的在评价左心室同步性上存在一定的相关性。Objective To assess the clinical value of RT-3DE and 2D-STI in evaluating left ventricular systolic function and synchrony in patients with CHD, And investigating the correlation of the two techniques. Methods 55 patients were divided into three groups according to the different results of coronary arteriongraphy. 2D-STI and RT- 3DE were performed on the 55 patients and 25 healthy subjects, LS, RS, CS, TAS POST were obtained, EDV, ESV, EF,Tmsv 16-SD% were obtained,the correlation of Tmsv-16-SD% and TAS-POST was analyzed. Results Compared with control group, parameters of sttidy groups were significant different（P〈0.05）. Among the study groups, some parameters were significant different. Tmsv-16-SD% and TAS-POST have positive correlation （r= 0. 794, P〈0. 001）. Conclusions RT-3DE and 2DSTI are useful methods in assessing LV systolic function and synchrony in patients with Coronary Heart disease of different coronary artery branch stenosis. There are various degree of correlations.

关 键 词：三维超声心动图 二维斑点追踪成像技术 冠心病 左心室收缩功能 同步性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R541.4[医药卫生—诊断学]