超选择性子宫动脉栓塞治疗子宫腺肌病不孕26例临床分析  

The Clinical Analyses of Super-choice Uterine Arterial Embolization in Treatment of Infertility Due to Adenomyosis

作　　者：王晓云[1] 

机构地区：[1]东营市胜利医院妇产科,山东东营257055

出　　处：《潍坊医学院学报》2012年第5期354-357,共4页Acta Academiae Medicinae Weifang

摘　　要：目的评价超选择性子宫动脉栓塞术对治疗子宫腺肌病患者不孕的临床疗效。方法选择26例生育期并且因为子宫腺肌病为不孕唯一原因的患者，年龄24～40岁，以Seldinger技术完成双侧子宫动脉上行支选择性插管，造影证实后用KMG进行栓塞，观察术后3个月、6个月、12个月的月经量、痛经程度、子宫体积变化、血清性激素的变化（同时选择25例生育期健康的女性为对照组），术后3个月即开始自然受孕，以12个月为观察期限，以最终受孕为疗效观察结果。结果子宫腺肌病患者行超选择性子宫动脉栓塞术治疗后月经量明显减少（P〈0．01），痛经减轻程度（P〈0．01），子宫体积变化（P〈0．01），血清性激素观察提示卵巢功能未受到影响，能够进行正常排卵，接受治疗的患者中共16例达到最终受孕目的，临床有效率达到6L53％．结论超选择性子宫动脉栓塞术治疗因为子宫腺肌痛导致不孕的临床效果较为满意，对卵巢功能无明显影响。Objective To assess the clinical efficacy of super-choice uterine arterial embolization（UAE） in treatment of infertil- ity due to adenomyosis. Methods The study included 26 childbearing women whose sterile reason was attributed to adenomyosis, and 25 women of ehildbearing age were also recruited in a healthy control group. The super-choice UAE was performed in patients with adenomyosis. The kelt mierosphere gelatin（KMG） for vascular embolization mixed with antibiotics were used to embolize arteries. The degree of dysmenor- rheal,amount of menorrhea, uterine volume and serum sex hormone of two groups were investigated in the third,sixth and twelfth month after the operation. The success of becoming pregnant was observed as the positive result of the treatment. Results The degree of dysmenorrheal, amount of menorrhea and Uterine volume in adenomyosis group were significantly better than that in control group after operation（ P 〈 0.01 ）. The observation of serum sex hormone also indicated that the ovarian function was normal. As the result of treatment,16 sterile women succee- ded in becoming pregnant. Conclusion Super-choice UAE has a good effectiveness in treatment of infertility due to adenomyosis.

关 键 词：子宫腺肌病 超选择子宫动脉检塞术 不孕 血清性激素 

分 类 号：R711.71[医药卫生—妇产科学]