孕期血像的变化与产后输血的相关性研究  

Correlation of Hemogram Changes During Pregnancy of Healthy Women with Postpartum Blood Transfusion

作　　者：李卉[1] 陈麟凤[1] 王淑英[1] 王彦[1] 师红梅[1] 汪德清[1] 

机构地区：[1]解放军总医院输血科,北京100853

出　　处：《中国实验血液学杂志》2012年第5期1240-1242,共3页Journal of Experimental Hematology

基　　金：卫生部行业专项课题(编号201002005)

摘　　要：本研究旨在探讨健康孕妇孕期血像的变化与产后输血的相关性。收集2008年在我院待产孕妇的门诊信息和住院信息,追踪孕妇从怀孕第4个月到第10个月每月的血常规检查结果,产前肝肾功能、凝血功能。筛选产前无基础疾病且非高龄单胎孕妇作为研究对象,将其分为产后输血组与非输血组,研究孕期白细胞(WBC)计数、血红蛋白(Hb)水平、血小板(Plt)计数、血小板比积(PCT)、平均血小板体积(MPV)、血小板分布宽度(PDW)在两组之间是否具有显著差异。结果表明,2008年在我院产科待产住院450人,其中输血68人,具有完整产前资料的输血产妇30人;与同期非输血产妇28人比较,结果显示两组Hb、Plt、PCT、MPV、PDW均正常,两组之间血象变化无显著差异。但Hb水平与Plt计数在孕末期均有轻微下降,Plt计数变化与PCT、MPV、PDW之间无相关性。结论:健康孕妇孕期血像的变化与产后出血、输血无相关性,孕妇Hb与Plt在孕末期均有轻微下降,但Plt计数、PCT、MPV和PDW均在正常范围内。This study was aimed to explore the correlation of hemogram changes during pregnancy of healthy women with postpartum blood transfusion.The outpatient and inpatient information of expectant lying-in women in our hospitals was collected,the route blood test,lever and kidney function and blood coagulation function tests were performed from the 4th to the 10th month of pregnancy.The pregnant women without underlying diseases and non-eldery pregnant women with single fetus were selected as the subjects of study.They were divided into pospartum blood transfusion group and non-blood transfusion group.The white blood cell（WBC） count,hemoglobin（Hb） level,platelet（Plt） count,plateletocrit（PCT）,mean platelet volume（MPV）,platelet distribution width（PDW） were compared in 2 groups.The results showed that 68 cases out of 450 expectant lying-in women received blood transfusion,among them 30 cases with complete data of puerperal transfusion were taken as blood transfusion group,the 28 cases of non transfusion puerperal as control group.There was no significant difference of hemogram changes between the two groups.However,there was a slight decline in Plt count and Hb level of late pregnant women.What is more,there was no correlation between Plt count change and the PCT,MPV and PDW.It is concluded that the changes of hemogram during pregnancy has no correlation with postpartum hemorrhage and blood transfusion in healthy pregnant women,the Plt count and Hb level of pregnant women slightly decline.Nevertheless,PCT,MPV and PDW are within the normal range.

关 键 词：妊娠 血像 输血 

分 类 号：R457.1[医药卫生—治疗学]