电针不同频率和取穴对膀胱逼尿肌功能减弱的调节效应差异研究  

Regulation Effects of Electroacupuncture of Different Frequencies and Acupoints on Weakened Detrusor Function

作　　者：韩静[1] 叶笑然[1] 孟宪军[2] 陈玄[1] 黄晓卿[1] 

机构地区：[1]福建省中医药研究院,福建福州350003 [2]厦门大学医学院中医系

出　　处：《世界中医药》2012年第5期427-430,共4页World Chinese Medicine

基　　金：福建省中医药研究院自主选题项目(编号:2012fjyyk-1);福建省卫生厅中医药科研重点课题(编号:WZZQ0902)

摘　　要：目的:探讨电针不同频率和取穴调节膀胱逼尿肌功能减弱的效应差异,为电针治疗排尿障碍症穴位及电针参数的选择提供依据。方法:100只新西兰兔随机分为对照组、模型组、电针组(据穴位及电针频率分为中极2Hz和100Hz、三阴交2Hz和100Hz、曲池2Hz和100Hz6个亚组)。静脉输注0.05%山莨菪碱建立逼尿肌功能减弱模型,检测指标为各组充盈期膀胱内压波形及排尿期分时排尿速度。结果:1)中极2Hz、三阴交2Hz、曲池2Hz、三阴交100Hz组的排尿初速度显著大于模型组(P<0.05);2)所有2Hz电针组排尿速度随时间下降的速率均大于模型组(P<0.05);3)2Hz电针不同穴位加快初始排尿速度的效应存在穴位差异性,效应大小依次为:三阴交=中极>曲池。结论:1)电针可显著加快逼尿肌功能减弱模型排尿期的排尿速度;2)2Hz电针加快排尿速度的效应优于100Hz电针,且效应存在穴位差异性,三阴交和中极穴优于曲池穴。Objective：To explore the regulation effects of electroacupuncture（EA） with different frequencies and acupoints selection on weakened detrusor function, to provide scientific basis for acupoints and EA parameters selecting in clinical practice of acupuncture treat- ment for micturition disorders. Methods：One hundred New Zealand rabbits were randomly divided into control group, model group and EA groups （which were divided into 6 subgroups according to the aeupoints and EA frequency selection： Zhongii 2Hz, Zhongji 100Hz, Sanyinjiao 2Hz, Sanyinjiao 100Hz, Quchi 2Hz, and Quchi lOOHz ）. The model of weakened detrusor function was established by intra- venous infusion of 0.05% scopolamine. Intravesical pressure was recorded through continuous cystometry and urination flow rate in each group was recorded. Results ： 1 ） Groups of Zhongji 2Hz, Sanyinjiao 2Hz, Quchi 2Hz and Sanyinjiao 100Hz had significantly faster speed of initial urination than the model group （ P 〈0.05） ; 2）The micturition speed decrease with time in all the 2Hz EA groups were quic- ker than that in the model group （ P 〈 O. 05 ） ; 3 ）2Hz EA at different acupoints sped up the initial urination to different degree： Sanyin- jiao = Zhongji 〉 Quchi. Conclusion： 1 ）EA could significantly accelerate the urination speed in weakened detrusor function model; 2 ） The effects of 2Hz EA is better than 100Hz EA at accelerating mieturition speed, and the effects are acupoins specific ： EA at Sanyin- jiao and Zhongji are better than EA at Quchi.

关 键 词：电针 电针频率 逼尿肌 排尿障碍 穴位 

分 类 号：R697.32[医药卫生—泌尿科学]