临床药师对2例异基因外周血干细胞移植患者的药学监护  

Pharmaceutical Care for 2 Cases of allo-PBSCT by Clinical Pharmacist

作　　者：方琴[1] 马丹[1] 王季石[2] 孙志强[2] 卢英豪[2] 朱丹[3] 胡秀英[2] 李燕[2] 王娅婷[2] 

机构地区：[1]贵阳医学院附属医院药剂科,贵阳550004 [2]贵阳医学院附属医院血液科,贵阳550004 [3]贵阳医学院药学院,贵阳550004

出　　处：《中国药房》2012年第42期4019-4021,共3页China Pharmacy

摘　　要：目的:探讨临床药师在异基因外周血干细胞移植(allo-PBSCT)患者临床治疗中发挥的作用。方法:通过临床药师对2例allo-PBSCT患者实施药学监护,参与制订治疗方案,全程参与临床查房、病例讨论,对患者进行药学监护和用药教育。结果:A患者allo-PBSCT术后第11天,血常规提示造血重建;期间监测巨细胞病毒(HCMV-DNA)结果呈阴性;骨髓细胞学示骨髓增生明显活跃;患者生命征平稳,无发热等不适反应。B患者allo-PBSCT术后第11天,血常规提示造血重建。期间监测HCMV-DNA结果呈阴性;骨髓细胞学示粒系增生,红系增生低下;患者无发热、皮疹等移植物抗宿主病(GVHD)表现。结论:临床药师通过参与allo-PBSCT患者的药学监护,协同医师制订用药方案,可提高医师、护士和患者对临床药师的认可,减少药品不良反应,提高药物治疗效果,体现临床药师的价值。OBJECTIVE： To study the role of clinical pharmacists in the treatment for patients with allogeneic peripheral blood stem cell transplantation （allo-PBSCT）. METHODS： Clinical pharmacists provided pharmaceutical care for 2 cases of allo-PBSCT, participated in the formulation of therapeutic plan, ward-round and case discussion, and carried out pharmaceutical care and medica- tion education. RESULTS： 11 days after allo-PBSCT, routine blood test of patient A reminded hematopoietic reconstruction; HC- MV-DNA was negative; bone marrow inspection showed active bone marrow hyperplasia; the vital signs of patients were stable without fever and other ADR. 11 days after allo-PBSCT, routine blood test of patient B reminded hematopoietic reconstruction; HC- MV-DNA was negative; bone marrow inspection showed myeloid cell hyperplasia and low erythroid cell hyperplasia; no fever, ery- thra and other GVHD manifestation were found. CONCLUSION： Through clinical pharmacists participate in pharmaceutical care for alIo-PBSCT patients, and collaborate with doctors on medical plan to improve the acceptance of doctors, nurses and patients for clinical pharmacists and realize the value of them.

关 键 词：临床药师 异基因外周血干细胞移植 药学监护 

分 类 号：R979.1[医药卫生—药品] R969.3[医药卫生—药学]