急性冠脉综合征合并高血压患者PCI术后血浆脑钠肽对心功能评价的研究  

Study of the Plasma BNP on Cardiac Function Evaluation in ACS Patients with Hypertension after PCI Operation

作　　者：游向东[1] 邸龙辉[1] 侯冰洁 马亚洁[1] 耿娟[1] 王玉宵 

机构地区：[1]河北省保定市唐县人民医院,072350

出　　处：《实用心脑肺血管病杂志》2012年第11期1810-1811,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的探讨血浆脑钠肽(BNP)水平与急性冠脉综合征(ACS)合并高血压患者经皮冠状动脉介入治疗(PCI)术后与心功能的关系。方法检测42例ACS合并高血压患者和38例ACS患者行PCI术后血浆BNP水平,随访观察6个月,检测心功能。结果试验组血浆BNP水平明显低于对照组(P<0.05),随访6个月试验组心功能水平明显高于对照组(P<0.05)。结论 ACS患者血浆BNP水平在早期即明显升高,是患者复合心血管事件危险性的独立预测因子,有创干预能明显减少ACS患者的复合心血管事件。血浆BNP水平对ACS合并高血压患者PCI疗效、心功能状态有很好的预测意义。Objective To investigate the outcome prediction of ACS and hypertension patients influnced by observing the changes of Plasma BNP after PCI.Methods Plasma BNP levels in 42 patients of ACS with hypertension after treatment with PCI,All patients were followed up and detect cardiac function for an average 6 months.Results BNP levels in the patients with PCI were lower than that in the patients with no PCI（P〈0.05）,Cardiac function levels in the patients with PCI were higher than that in the patients with no PCI（P〈0.05）.Conclusion Plasma BNP levels increased significantly in ACS patients in early.It was one of Independent Predictor in Cardiac event.PCI could reduce Cardiac risk event.Detection of plasma BNP might have prognostic value for therapeutic effect and Cardiac function in the patients of ACS and hypertension after PCI.

关 键 词：血浆脑钠肽 急性冠状动脉综合征 高血压 血管成形术 经腔 经皮冠状动脉 心功能 

分 类 号：R541.4[医药卫生—心血管疾病] R544.1[医药卫生—内科学]