猪博卡病毒流行病学研究  

Research on the Epidemiology of Porcine Bocavirus

作　　者：郝飞[1] 汤德元[1] 李春燕[1] 罗险峰[2] 张华[2] 马萍[2] 曾智勇[1] 洪尼宁[2] 刘霞[2] 

机构地区：[1]贵州大学动物科学学院,贵阳550025 [2]贵州省动物疫病预防控制中心,贵阳550008

出　　处：《畜牧兽医学报》2012年第10期1609-1617,共9页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：贵州省2011年农业攻关项目资助[黔科合NY字(2011)3103号];贵州省2010年农业科技攻关项目(黔科合NY字[2010]3042号)

摘　　要：猪博卡病毒属于细小病毒科细小病毒亚科博卡病毒属单链线性DNA病毒,该病毒于2009年在瑞典发现。作为一种新型病毒,人们对其的研究仍处于初步探索阶段。本文从博卡病毒的由来、猪博卡病毒的发现、分类、基因组结构及流行病学等方面进行阐述,并根据GenBank收录的25条猪博卡病毒的部分基因和全基因序列,利用DNAStar分析软件,通过Jotun-Hein算法,分别从猪博卡病毒的NS、NP、VP以及全基因序列进行相似性临近排组分析,并建立了PBoV系统发育树。结果发现可将猪博卡病毒分为2个大支和若干遗传簇,但这些不同的遗传簇所包含的毒株在核苷酸序列上仍然存在着一定的差异。The Porcine Bocavirus was found in Sweden in 2009, which belongs to Parvovirus sub- family, Parvoviridae with single-stranded DNA. As a new kind of virus, the studies on Porcine Bocavirus is in the stage of preliminary exploration by humans. The paper has described the source, discovery, classification, genome and epidemiology of Porcine Bocavirus. According to the GenBank including partial and complete gene sequences of 25 Porcine Bocaviruses, we put analysis of arranging the group of homology on NS, NP, VP and complete gene sequences about PBoV with analysis software of DNAStar, arithmetic Jotun-Hein. And we established the PBoV system of Phylogenetic tree. The result revealed that the PBoV includes two large branches and many hereditary clusters. But there are some differences in the nucleotides sequences of different hereditary clusters containing strains.

关 键 词：猪博卡病毒 分子流行病学 遗传进化分析 

分 类 号：S852.659.2[农业科学—基础兽医学]