鼻腔鼻窦结外Rosai-Dorfman病1例  

One case report of Rosai-Dorfman disease in nasal cavity and nasal sinuses

作　　者：保国华[1] 康晶[1] 邵辉[1] 

机构地区：[1]宁夏医科大学总医院耳鼻咽喉头颈外科,银川750004

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第21期1007-1008,共2页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：1病例报告患者,男,42岁。因左侧鼻塞8年余,伴头痛、头晕1年,加重2个月就诊我院。患者8余年前＂感冒＂后开始出现左侧鼻塞、流涕症状,鼻塞呈间断性,无头痛、头昏不适,当地医院以＂鼻-鼻窦炎＂给予滴鼻药、抗生素及中成药治疗1周,症状无明显缓解。近1年，患者自觉左侧鼻塞症状进行性加重，呈持续性，Rosai-Dorfman disease in nasal cavity and nasal sinuses is known as an idiopathic proliferattive disease of histiocytes with a distinct morphologoic feature and is very rare. It is easy to relapse and be misdiagnosed.In on case, the infiltrating histiocytes had large round or oval nuclei. The cytoplasm was abundant, granular or vaeuolated and foamy. Immunohistoehemieal studies showed that the histiocytes were strongly reactive with antibodies against S100 and CD68. The diagnosis of extranodal RDI） in the paranasal sinuses could be differentiated with rhinoscleroma, eosinophilic granuloma, plasmacytoma, or fibrous histiocytoma. It showed that the identification of the distinctive histoeytes which are typically immunoreactive to S100 and CD68 can be quite helpful for correct diagnosis.

关 键 词：ROSAI-DORFMAN病 病理检查 外科手术 

分 类 号：R765.9[医药卫生—耳鼻咽喉科]