贵州省巴马森林病毒和罗斯河病毒感染的调查研究  

Investigation of infection with Barmah Forest virus and Ross River virus in Guizhou province,China

作　　者：叶绪芳[1] 付士红[2] 高晓艳[2] 赵苏晔[1] 刘淳婷[1] 王环宇[2] 吴升伟[1] 梁国栋[2] 

机构地区：[1]贵州省疾病预防控制中心免疫规划所,贵州贵阳550004 [2]中国疾病预防控制中心病毒病预防控制所,传染病预防控制国家重点实验室,北京102206

出　　处：《中国媒介生物学及控制杂志》2012年第5期428-431,共4页Chinese Journal of Vector Biology and Control

基　　金：中美新发和再发传染病合作项目(U19-GH000004)~~

摘　　要：目的了解贵州省虫媒病毒中巴马森林病毒(BFV)、罗斯河病毒(RRV)的感染现状,为不明原因病毒性脑炎防治工作提供科学依据。方法 2005-2008年在贵州省采集不明原因发热和病毒性脑炎病例检测BFV、RRV IgM抗体,并对2007年健康人群进行BFV、RRV IgG抗体检测。结果①共检测204例不明原因发热病例BFV和RRV IgM抗体,BFV IgM抗体阳性4例,阳性率1.96%,RRV阳性6例,阳性率2.94%;②共检测426例病毒性脑炎病例BFV和RRV IgM抗体,BFV IgM抗体阳性12例,阳性率2.82%,RRV阳性15例,阳性率3.52%;③共检测870份健康人群BFV、RRV IgG抗体,BFV IgG抗体阳性率1.49%,RRV IgG抗体阳性率1.15%;④地区分布显示,2005-2008年BFV、RRV IgM抗体阳性病例数和分布县数呈逐年增加趋势。结论贵州省可能存在由BFV和RRV感染引起的疾病,应加强对这两种病毒引起的相关疾病监测和研究工作。Objective To investigate the infection with Barmah Forest virus （BFV） and Ross River virus （RRV） among arboviruses in Guizhou province, China, and to provide scientific basis for prevention and control of viral encephalitis of unknown origin. Methods BFV and RRV IgM antibodies were detected in patients with unexplained fever and viral encephalitis from 2005 to 2008 in Guizhou Province, and BFV and RRV IgG antibodies were detected in healthy persons in 2007. Results Out of the 204 cases with unexplained fever examined, 4 （1.96%） had BFV IgM antibody, and 6 （2.94%） had RRV IgM antibody. Out of the 426 cases with unexplained viral encephalitis examined, 12 （2.82%） had BFV lgM antibody, and 15 （3.52%） had RRV IgM antibody. Out of the 870 healthy persons examined, 1.49% had BFV IgG antibody, and 1.15% had RRV IgG antibody. The number of BFV/RRV IgM-positive cases and the number of counties with positive cases increased year by year from 2005 to 2008. Conclusion There might exist some diseases caused by BFV and RRV infection in Guizhou province, China, and we should strengthen monitoring and research work for the diseases caused by the two viruses.

关 键 词：巴马森林病毒 罗斯河病毒 IGM抗体 IGG抗体 

分 类 号：R373.3[医药卫生—病原生物学]