元参组方对急性辐射损伤的保护机理研究  

Mechanism Research of Yuanshen composing prescriptions on acute radiation injury protection

作　　者：曾婷[1] 郝丽[1] 金星[2] 路松毅 谢逸欣[1] 马丽[1] 刘保昌[1] 

机构地区：[1]广州军区疾病预防控制中心 [2]76160部队 [3]广东省卫生监督所

出　　处：《中国中医基础医学杂志》2012年第10期1096-1097,共2页JOURNAL OF BASIC CHINESE MEDICINE

摘　　要：目的:观察元参组方对急性放射损伤的保护作用及其作用机理。方法:以X射线照射小鼠全身引起辐射损伤,观察元参组方对辐射小鼠白细胞、骨髓有核细胞数、粒系造血祖细胞和脾脏指数的影响。结果:元参组方对正常小鼠和受照小鼠白细胞、骨髓有核细胞数、造血干细胞和粒系造血祖细胞有明显的升高作用,疗效高于"养血饮"。结论:元参组方能促使造血干细胞的增殖与分化,对急性放射性损伤有显著治疗作用。Objective To observe the protective effect of Yuanshen composing prescriptions on acute radiation injury. Methods The model was made in mice by X-ray radiation. The white blood cells （WBC） , bone marrow nucleated cells （BMNC） , CFU-G, CFU-S were measured. Results Yuanshen composing prescriptions could increase WBC, BMNC, CFU- G and CFU-S. The effect was higher than ＂Nourishing drink＂. Conclusion： Xuanshen composing prescriptions can promote proliferation and differentiation of Hematopoietic stem cells and have significant treatment effect on acute radiation injury.

关 键 词：元参组方 急性辐射损伤 造血干细胞 

分 类 号：R285.5[医药卫生—中药学]