类风湿关节炎中医发病学初探  

Primary Exploration of the Pathogenesis of Rheumatoid Arthritis in Traditional Chinese Medicine

作　　者：彭江云[1] 狄朋桃[1] 方春凤[1] 李兆福[1] 刘维超[1] 徐翔峰[1] 

机构地区：[1]云南中医学院第一附属医院,云南昆明650021

出　　处：《世界中西医结合杂志》2012年第10期857-859,868,共4页World Journal of Integrated Traditional and Western Medicine

基　　金：国家中医药管理局科研专项(No.06-07JP43)

摘　　要：目的探讨当前类风湿关节炎(RA)的发病学规律。方法对2006～2010年间云南不同地区的1120例RA患者的一般情况、病史、伴随症状、体征等进行调查,用计数资料的统计描述方法进行分析。结果调查结果显示,1120例患者中,求诊率随年龄增加而增加,RA患者存在明显的的性别差异;职业与工作强度调查结果是相对应的;体质中平和质最多(32.50%),虚性体质构成比之和为36.43%,湿热质11.16%,痰湿质9.29%,瘀血质(3.21%)最少;发病诱因主要以受寒为多见,最常见的症状与体征依次为痛有定处、得热痛减、遇寒痛增、痛处拒按、冷痛而肿等。结论当代社会条件下RA发病学规律有以下几个方面:阴阳受损、营卫不和、气血亏虚是疾病发病的内因;六淫邪气是RA发病的外部因素;过劳、饮食不节是不可忽视的因素之一;痰浊瘀血是内源性致病因素。在辨证过程中要准确把握疾病的病因病机要点。Objective To explore the current rule of the pathogenesis of rheumatoid arthritis（RA）.Methods From 2006 to 2010,1120 patients of RA in different regions of Yunnan were investigated in terms of the general situation,medical history,associated symptoms,physical signs and the others.The statistical descriptive method of enumeration data was adopted in analysis.Results Among 1120 patients,the visit rate was increased along with the age increase,the apparent difference presented in the sex of RA patients and the results of occupation were coincident with those of the working strength.Concerning to the body constitution,the neutral constitution accounted for 32.50%,the sum of the constituent ratio of deficiency constitution was 36.43%.Damp heat constitution accounted for 11.16%,phlegm damp constitution for 9.29% and blood stasis constitution for 3.21%.The invasion of cold was the common inducer.The most commonly seen symptoms and physical signs in sequence were fixed pain,alleviation on heat,aggravation on cold and pressure,cold pain with swelling,etc.Conclusion In the current social condition,the rule of RA pathogenesis includes：the damage of yin and yang,disharmony of ying and wei,deficiency of qi and blood are the internal factors of the disease;the six exogenous factors are the external factors of the disease;overstrain,stress and improper diet are the assignable factors;and phlegm and blood stasis are the endogenous causative factors.It is required to grasp the keys on the etiology and pathogenesis accurately in pattern/syndrome differentiation.

关 键 词：类风湿关节炎 中医 发病学 

分 类 号：R593.22[医药卫生—内科学]