原发三叉神经痛神经根部蛛网膜变化的病理研究  

Pathological research of the nerve roots arachnoid change for Primary trigeminal neuralgia

作　　者：李继禄[1] 姬广福[1] 钱运[1] 张新华[1] 牛立建[1] 张宁宁[1] 

机构地区：[1]泰山医学院附属医院神经外科,山东泰安271000

出　　处：《泰山医学院学报》2012年第8期573-574,共2页Journal of Taishan Medical College

摘　　要：目的探讨原发三叉神经痛神经根部蛛网膜病理变化。方法对43例实验组原发三叉神经痛神经根部蛛网膜和21例对照组颅脑外伤患者近侧裂或侧裂部的蛛网膜送病理检查,采用SPSS软件,运用卡方检验对两组资料的慢性炎性细胞浸润、水肿、钙化的阳性率进行比较,再进一步将慢性炎性细胞浸润、钙化例数二者行两两对比。结果两组慢性炎性细胞浸润、钙化的阳性率的卡方检验P<0.05,二者有显著差异,水肿阳性率无差异;慢性炎性细胞浸润、钙化例数二者行两两对比,P<0.05,差异有统计学意义。结论原发三叉神经痛患者神经根部周围环境中存在炎性反应,炎性反应存在可使局部水肿、长期存在可形成钙化。Objective： To investigate the pathological changes of nerve roots araehnoid for primary trigeminal neuralgia. Methods ： By forty-three cases of the experimental group nerve roots arachnoid for primary trigeminal neuralgia and twenty-one cases of cleft or sylvian Department arachnoidin in the control group of patients with traumatic brain injury proximal sent for pathological examination, we compare the positive rate of edema, calcification, and further line twenty-two contrast of the number of eases of both chronic inflammatory cell infiltration, calcification by SPSS software, using the ehi-square test of the two groups chronic inflammatory cell infiltration of the data. Results ： The two groups of chronic inflammatory cell infiltration, the positive rate of calcification of the ehi-square test, P 〈 0.05, significant differences edema positive rate was no difference of between the two; chronic inflammatory ceU infiltration, the calcified number of eases of both line twenty-two contrast, P 〈 0. 05, the difference was statistically significant. Conclusion ： The surrounding environment of nerve roots in patients with the primary trigeminal neuralgia, is present of inflammatory reaction, and the inflammatory response in the presence of local edema can exist for a long time and can be formed calcification.

关 键 词：三叉神经痛 蛛网膜 结构紊乱 炎性反应 水肿 钙化 

分 类 号：R745.11[医药卫生—神经病学与精神病学]