人参皂苷Rg3抗肿瘤及其作用机制研究进展  

A Review on the Anti-tumor Effects and Mechanism of Ginsenoside Rg3

作　　者：张晓平[1] 马大龙[1] 陈新梅[1] 

机构地区：[1]山东中医药大学药学院,山东济南250355

出　　处：《中国执业药师》2012年第11期52-56,共5页China Licensed Pharmacist

基　　金：山东省高等学校科技计划项目(J09LF56)

摘　　要：人参皂苷Rg3是人参中的一种稀有活性成分,应用广泛。本文就人参皂苷Rg3诱导肿瘤细胞凋亡,抑制肿瘤细胞增殖和血管生成,逆转肿瘤细胞的耐药作用,增强肿瘤患者免疫能力,改善患者生活质量等方面,总结人参皂苷Rg3抗肿瘤作用及其相关机制的研究进展,为抗肿瘤新药的开发奠定基础。Ginsenoside Rg3 is one of the biologically active components, which rarely exists in ginseng, and has been used widely. It can induce the apoptosis of tumor cell, resist the proliferation of tumor cell and formation of new blood vessel, reverse the multi-drug resistance of tumor cells, improve the human immunity and improve life quality of the patients. This article discussed its anti-tumor effects and the relative mechanism. The research on ginsenoside Rg3 will provide a basis for the development of new anti-tumor drugs.

关 键 词：人参皂苷RG3 肿瘤 作用机制 

分 类 号：R979.1[医药卫生—药品]