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作 者:曹汉钧[1] 金小林[1] 徐祥珍[1] 江文才[1] 沈明学[1] 梅火根 高金兵 邰鸿奎 李叶芳[5] 杜松如 李永春[7]
机构地区:[1]江苏省血吸虫病防治研究所,无锡214064 [2]江苏省吴江市疾病预防控制中心 [3]江苏省高邮市疾病预防控制中心 [4]江苏省兴化市疾病预防控制中心 [5]江苏省镇江市丹徒区疾病预防控制中心 [6]江苏省如皋市疾病预防控制中心 [7]江苏省建湖县疾病预防控制中心
出 处:《中国血吸虫病防治杂志》2012年第5期585-587,共3页Chinese Journal of Schistosomiasis Control
基 金:江苏省卫生厅项目(X200738)
摘 要:目的观察土源性线虫病控制后期群体化疗效果,为制定防治方案提供科学依据。方法将6个村分成目标化疗、选择性化疗和对照3个组,通过连续3年的观察,比较各组人群土源性线虫感染率、感染度和再感染情况,评价化疗效果。结果选择性化疗、目标化疗和对照组人群土源性线虫感染率化疗干预后比干预前分别下降85.94%、43.10%和20.87%;目标化疗组因部分重点人群菜地施用新鲜人粪致钩虫感染率高,影响了化疗效果;再感染率是新感染率的16.65倍。结论在土源性线虫病控制后期化疗干预仍有效果,但加强粪肥使用管理、开展对重点人群的健康教育更为重要。Objective To evaluate the effects and influencing factors of mass chemotherapy in the late stage of soil-borne ne-matodiasis control so as to provide the evidence for the development of control programs. Methods Six villages were divided into three groups: the target chemotherapy, the selective chemotherapy and the control. By observation in three consecutive years, the indexes, mass infection rates, infection degrees and re-infections of soil-borne nematodes, were compared among the 3 groups. The influencing factors were also analyzed. Results The population infection rates of soil-borne nematodes decreased by 85.94%, 43.10% and 20.87%, respectively, in the three groups after chemotherapy compared with those before the intervention. A higher hookworm infection rate appeared and the chemotherapy effect was impacted in the target chemotherapy group, as some key population applied fresh human waste in vegetable plots. The re-infection rate was 16.65 times of the new infection rate. Con-clusions Chemotherapy is still useful in the late stage of soil-borne nematode control. It is more important to enhance manage-ment of using manure and health education on focus population.
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