成人抑郁症患者儿童期受虐对神经系统软体征的影响  

Affect of the child abuse to the soft neurological signs in depressive patients

作　　者：牛威[1] 赵汉清[1] 仲爱芳[1] 丁松柏[1] 林芝[1] 

机构地区：[1]解放军第102医院全军精神医学中心,常州213003

出　　处：《临床精神医学杂志》2012年第5期316-318,共3页Journal of Clinical Psychiatry

摘　　要：目的:研究抑郁症患者儿童期受虐待对神经系统软体征的影响。方法:对103例抑郁症患者行儿童受虐问卷、神经系统软体征、汉密尔顿抑郁量表、自杀意念量表以及Beck绝望量表评定。结果:①儿童受虐患者较未受虐者额叶有更多的软体征(2.51±1.61,1.77±1.25,P<0.01)。有情感忽视患者额叶软体征也明显高于无情感忽视者(2.53±1.63,1.80±1.25,P<0.05);有躯体忽视者额叶较无躯体忽视者软体征明显增多(2.41±1.63,1.65±1.00,P<0.01);有性虐待患者软体征明显高于无性虐待者(6.29±1.83,4.28±2.82,P<0.01)。②受虐总分与额叶和颞叶评分呈明显正相关(r=0.29,P<0.01;r=0.24,P<0.05);情感受虐待、情感被忽视及躯体虐待与额叶评分呈明显正相关(r=0.284,0.345,0.218,P<0.01或0.05)。③HAMD与神经系统软体征总分及各脑叶均呈明显正相关;自杀意念量表评分与神经系统软体征总分及额叶、顶叶、颞叶软体征评分呈明显正相关。结论:抑郁症患者儿童期受虐对大脑有不利影响,不同虐待可对不同脑区产生损害,主要在额叶。Objective：To investigate the effects of child abuse on the soft neurological signs （SNS） in depressive patients.Method：103 depressive patients were tested by childhood trauma questionnaire（CTQ）,24-item Hamiltom rating scale for depression （HAMD）,self-rating idea of suicide scale （SIOSS） and Beck helpless rating scale （BHS） to evaluate the severity of symptoms.Patients were divided into abuse group （total score ≥55 or subscale score ≥13） and no-abuse group （55 or 13） in terms of CTQ score.Results：①The child abuse group have much more SNS than no-abuse group in frontal lobe（2.51±1.61 vs 1.77±1.25,P0.01）.The emotion neglect group have much more SNS in frontal lobe than no emotion abuse group （2.53±1.63 vs 1.80±1.25,P0.05）.The Body abuse group have much more SNS in frontal lobe than no body abuse （2.41±1.63 vs.1.65±1.00,P0.01）.The sexual abuse group have much more SNS in temporal lobe than no sexual abuse group （6.29±1.83 vs 4.28±2.82,P0.01）.②The SNS of frontal and temporal lobe were significantly associated with the child abuse （r=0.29 P0.01;r=0.24,P0.05）.The emotion abuse,emotion neglect and body abuse were significantly associated with the SNS of frontal lobe（r=0.284,P0.01;r=0.345,P0.01;r=0.218,P0.05）.③HAMD were significantly associated with the SNS of total and each brain lobe;SIOSS were significantly associated with SNS of total frontal parietal and temporal lobe.Conclusion：The child abuse can negatively influence the brain in depressive patients.Different kinds of abuses affect different lobes,especially the frontal lobe.

关 键 词：抑郁症 儿童虐待 神经系统软体征 

分 类 号：R749.4[医药卫生—神经病学与精神病学]