天津及周边地区胆道闭锁的流行病学调查  

Epidemiological investigation in Biliary Atresia of Tianjin and surrounding areas

作　　者：管志伟[1] 詹江华[1] 罗喜荣[1] 包国强[1] 宫济春[1] 

机构地区：[1]天津市儿童医院,天津市300074

出　　处：《临床小儿外科杂志》2012年第5期329-331,共3页Journal of Clinical Pediatric Surgery

基　　金：本研究为天津市地市级基金项目,项目号：11KG120

摘　　要：目的通过对本院近年来收治的胆道闭锁患儿临床资料的流行病学调查，分析天津及周边地区胆道闭锁的发病趋势。方法收集1995年1月至2011年12月作者收治的经术中胆道造影确诊的168例胆道闭锁患儿临床资料，通过检索病历、电话随访及门诊复查相结合的方式获得研究资料，进行流行病学调查。应用SPSS16.0统计学软件进行数据分析，以P〈0.05为差异有统计学意义。结果 ①天津及周边地区胆道闭锁的发病率呈现逐年上升趋势。 ②天津市各郊县基层医院发现或怀疑胆道闭锁并转诊的患儿数量呈现明显差异。 ③首次就诊于基层医院的患儿平均手术年龄明显高于首次就诊于本院的患儿（P≤0.05），平均手术年龄呈现逐年降低趋势。结论近年来胆道闭锁的发病率明显升高，手术年龄明显降低，分析原因可能与迅速上升的经济水平、不断增强的健康意识及广大家长和医师对胆道闭锁认识的提高有密切关系。Objective Using epidemiologieal investigation method to explore the trend of incidence of biliary atresia in Tianjin urban and suburban,we have collected the clinical data of biliary atresia from Tianjin Children＇ s hospital in recent years. Methods The clinical data of biliary atresia patients from January 1995 to December 2011 were reviewed and analyed. By retrieving cases, telephone or out -patient follow-up to obtain research data. Statistical analysis was performed using SPSS 16.0 statistical software. Results （1）The incidence rate of biliary atresia was increased year by year in Tianjin. （2）The number of Tianjin suburban primary hospitals children with biliary atresia from Tianjin suburban primary, hospitals was different significantly. （3）The average age at surgery, of children with biliary atresia from primary hospital was significantly higher than the children which received by our hospital for the first time （ P ≤0.05 ） ; Meanwhile, the overall average age at surgery was reduced year by year. Conclusion The number of Biliary Atresia incidence increased, the age of doing Kasia Opcrtation in Biliary Atresia reduced year after year in recent years. It is associated with a rapid increased economic level, growing health awareness and improved understanding of biliary atresia.

关 键 词：胆道闭锁/流行病学 队列研究 

分 类 号：R595.7[医药卫生—内科学]