冠心病患者超敏C反应蛋白及总胆红素检测的临床意义  

Clinical significance of serum total bilirubin and Hs-CRP in patients with coronary heart disease

作　　者：钟志娟[1] 许坚锋[1] 陈红涛[1] 李冬梅[1] 郭国威[1] 

机构地区：[1]中山大学附属第五医院检验科,广东珠海519000

出　　处：《检验医学与临床》2012年第20期2544-2545,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨冠心病(CHD)患者血清总胆红素及超敏C反应蛋白(hs-CRP)测定的临床意义。方法 60例冠心病患者及健康对照60例,用钒酸盐氧化法测定总胆红素,用透射比浊法测定hs-CRP浓度并做结果分析。结果冠心病患者血清总胆红素水平与健康对照组相比降低(P<0.05),hs-CRP水平与健康对照组相比增高(P<0.01)。结论血清总胆红素与冠心病的发生率呈负相关;血清C-反应蛋白与冠心病的发生率呈正相关。Objective To investigate the clinical significance of serum total bilirubin and high sensitivity C-re- active protein（hs-CRP） in the patients with coronary heart disease（CHD）. Methods The serum levels of total biliru- bin and hs-CRP were respectively determined by the vanadium-acid oxidation method and the transmission turbidime- try in 60 cases of CHD（CHD group） and 60 healthy individuals（control group）. Results The serum level of total bil- iruhin in the CHD group was decreased as compared with the healthy group（P^0.05） ,while the serum level of Hs- CRP was increased as compared with the healthy group（P〈0. 001）. Conclusion There is negative correlation be- tween serum total bilirubin level and the occurrence of CHD. There is positive correlation between hs-CRP and the occurrence of CHD.

关 键 词：冠心病 血清总胆红素 超敏C反应蛋白 

分 类 号：R512.6[医药卫生—内科学]