火炭母化学成分的研究  

Chemical Constituents from Polygonum chinensis L.

作　　者：任恒春[1] 万定荣[2] 谷婧[1] 邹忠梅[1] 

机构地区：[1]中国医学科学院&北京协和医学院药用植物研究所,北京100193 [2]中南民族大学,武汉430074

出　　处：《天然产物研究与开发》2012年第10期1387-1389,1411,共4页Natural Product Research and Development

基　　金：重大新药创制专项(2011ZX09307-002-01)

摘　　要：本文对火炭母的化学成分进行研究,为选择控制其质量的指标性成分提供依据。运用硅胶、葡聚糖凝胶Sephadex LH-20等手段进行分离纯化得到9个化合物,并通过NMR、MS等波谱方法鉴定其结构分别为:正三十二烷醇(1)、β-谷甾醇(2)、没食子酸甲酯(3)、胡萝卜苷(4)、没食子酸(5)、槲皮素(6)、槲皮苷(7)、金丝桃苷(8)和3-甲氧基-4-鼠李糖鞣花酸(9),其中化合物1和9首次从该属植物中分得,4和8首次从该植物中分得。To control the quality, the chemical constituents of the aerial part of Polygonum chinensis L. were studied. Nine compounds were isolated and purified by silica gel and Sephadex LH-20 chromatography, and their structures were identified as n-heptacosanol （ 1 ） ,β-sitosterol （ 2 ）, methyl gallate （3）, daucosterol （4）, gallic acid （ $ ）, quercetin （ 6 ）, quercitrin （7）,hyperoside （8） and 3-O-methy-lellagic acid 4-O-rhamnopyranoside （9） by spectroscopic analysis,respectively. Among them, compounds 1 and 9 were isolated from genus Polygonum for the first time, while 4 and 8 were isolated from this plant for the first time.

关 键 词：火炭母 蓼属 黄酮类 鞣花酸苷 

分 类 号：R284.2[医药卫生—中药学]