61例抗糖尿病药物不良反应报告分析  

Analysis of 61 Adverse Drug Reaction Reports of Antidiabetics in Diabetes Mellitus

作　　者：徐熠[1] 徐玲玲[1] 徐泯[1] 年华[1] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院药剂科,上海200437

出　　处：《药物流行病学杂志》2012年第10期485-487,共3页Chinese Journal of Pharmacoepidemiology

基　　金：上海医院药学科研基金资助(编号:2010-YY-02-15)

摘　　要：目的:分析我院抗糖尿病药物不良反应(ADR)发生的特点,为临床合理安全使用该药提供参考。方法:采用回顾性方法,对我院2009年9月～2011年9月临床上报的ADR报告进行统计分析。结果:抗糖尿病药物导致ADR病例61例,其中男30例(49.18%),女31例(50.82%);涉及药物共6类10种。ADR临床表现主要为神经系统(35.11%)、消化系统(21.28%)及心血管系统(14.89%)反应。结论:抗糖尿病药物可引发多系统的不良反应,应引起医护人员和患者的关注,注意监测。Objective：To analyze the features of adverse drug reaction（ADR） induced by antidiabetics in diabetes mellitus for reference of rational drug use in the clinic.Methods：61 ADR cases were collected from September 2009 to September 2011 and analyzed retrospectively.Results：Among 61 cases,there were 30 male cases（49.18%） and 31 female cases（50.82%）,the male and female ratio being 0.97∶ 1.The ADR reports were involved in 10 kinds of antidiabetic drugs.The clinical manifestations of ADR included the nervous system（35.11%）,digestive system（21.28%） and cardiovascular system（14.89%）.Conclusion：The antidiabetics often caused multisystemic ADRs,so more attention should be paid to avoiding the occurrence of ADR by medical staff and patients.

关 键 词：抗糖尿病药物 药品不良反应 监测 

分 类 号：R977.15[医药卫生—药品]