非洲135例疟疾回顾性分析  

Retrospective Analysis of 135 Cases of Malaria in Africa

作　　者：陈晓红[1] 王慧媛[1] 赵志刚[1] 

机构地区：[1]首都医科大学附属北京天坛医院药剂科,北京100050

出　　处：《药品评价》2012年第26期18-20,共3页Drug Evaluation

摘　　要：目的:了解非洲疟疾的临床特点、诊治方法及其转归。方法:分析135例疟疾患者的临床资料。结果:临床表现中,发热135例(100%),其中以贫血31例(22.96%),脾肿大27例(20.00%),腹泻21例(15.56%),呕吐19例(14.07%),咳嗽17例(12.59%),寒战7例(5.19%)等多种症状。135例均接受青蒿素类抗疟药的综合治疗,全部治愈。结论:非洲疟疾大多数是恶性疟,临床表现复杂多样且不够典型;尽早诊断、及时治疗是改善本病预后的关键;青蒿素类药物是治疗疟疾安全、有效的首选药物。Objectivo： It is to understand the clinical characteristics, treatment method and outcome of African malaria. Mothods： Clinical data of 135 malaria patients are analyzed. Results： Among the clinical manifestations, 135 cases （accounted for 100%） got fever, in which there were 31 patients with anemia （accounted for 22.96%）, 27 patients with splenomegaly （accounted for 20.00%）, 21 patients with diarrhea （accounted for 15.56%）, and 19 patients with vomiting （accounted for 14.07%）. All above were the most common clinical manifestations. Then there were such various symptoms as cough （17 patients, accounted for 12.59%）, chill （7 patients, accounted for 5.19%） and etc. 135 patients all accepted anti-malarial treatment with Artesunate drugs. All of these 135 patients are cured and no one died. Conclusion： Most African malaria is malignant and with a high incidence rate. What is more, the clinical manifestations are complicated and not typical. So early diagnosis and prompt treatment are the key to improve the disease prognosis. Artesunate drugs are safe, effective and could be the first choice to treat malaria.

关 键 词：疟疾 治疗 青蒿素类药物 恶性疟疾 

分 类 号：R531.3[医药卫生—内科学]