水迷宫实验中不同性别树鼩学习记忆能力的比较  

Comparison of learning and memory abilities of male and female Tupaia tested by Morris water maze

作　　者：陆彩霞[1] 罕园园[1] 仝品芬[1] 江勤芳[1] 代解杰[1] 

机构地区：[1]中国医学科学院/北京协和医学院医学生物学研究所,昆明650118

出　　处：《中国实验动物学报》2012年第5期74-76,79,共4页Acta Laboratorium Animalis Scientia Sinica

基　　金："十一五"国家科技支撑计划项目(2009BAI83B02;2011BAI15B01);云南省科技基础条件平台建设计划项目(2006PT07-2)

摘　　要：目的研究雌雄树鼩空间学习和记忆能力的差异。方法随机选择自繁F1代树鼩20只(雄11只,雌9只),在相同条件下进行8 d的水迷宫实验,包括前7 d的定位航行实验和第8天的空间探索实验。结果定位航行实验中雌雄逃避潜伏期、游泳总路程差异无显著性(P>0.05),但不同时间水平差异有显著性(P<0.05);平均游泳速度雌雄差异无显著性(P>0.05)。空间探索实验中目标象限游泳时间和总时间之比、目标象限游泳路程和总路程之比雌雄差异无显著性(P>0.05);穿越目标象限次数和搜索策略雌雄差异有显著性(P<0.05)。结论水迷宫实验中树鼩在空间学习能力上雌雄无差异,但在空间探索实验中雄性的表现优于雌性。Objective To study the differences of learning and memory abilities between male and female Tupaia tested by Morris water maze.Methods Navigation test and probe test were performed to determine the learning and memory abilities in male and female Tupaia.Result There were no significant differences in the latency and total distance（P0.05） between male and female tupaia,but there were significant differences in number of crossing target quadrant and search strategy（P0.05）.Conclusions There is no significant difference in navigation test between males and females,but the performance of spatial probe is better in male than in female Tupaia tested by Morris water maze.

关 键 词：树鼩 水迷宫 性别 学习能力 记忆能力 

分 类 号：Q95-33[生物学—动物学]