复方黄柏液保留灌肠治疗溃疡性直肠炎的临床疗效  

Retention Enema with Compound Phellodendron Solution in the Treatment of Ulcerative Rectitis： Clinical Effects

作　　者：张磊[1] 李贵信[1] 刘艳贞[1] 闫志新[1] 

机构地区：[1]山东省德州市人民医院,山东德州253000

出　　处：《中国肛肠病杂志》2012年第10期33-35,共3页Chinese Journal of Coloproctology

摘　　要：为观察复方黄柏液保留灌肠治疗溃疡性直肠炎的临床疗效，本研究将120例溃疡性直肠炎患者随机分为两组，各60例，一组给予复方黄柏液保留灌肠治疗（治疗组），一组给予甲硝唑、柳氮磺吡啶、地塞米松、利多卡因混合液保留灌肠治疗（对照组），均每晚1次，15d为一疗程。治疗2个疗程后，比较两组患者总有效率、肠黏膜改善情况及复发率。结果显示，两组总有效率（96．7％VS90．0％）差异无统计学意义，P〉0．05；但在肠黏膜改善情况（98．3％VS78．3％）及复发率（6．7％VS31．7％）方面治疗组均明显优于对照组，P〈O．05。结果表明，两种方法治疗溃疡性直肠炎总体疗效相当，但复方黄柏液保留灌肠使用更方便，肠黏膜改善更明显，复发率更低，值得临床推广应用。Abstract This study was to observe the clinical effects of retention enema with compound phellodendron solution for treating ulcerative rectitis. The 120 cases of this disease were randomly divided into two groups,60 cases per group;i, e treatment group was given with compound phellodendron solution,control group with the mixture solution of metronidazole, salazosulfapyridine~ dexamethasone and lidocaine; retention enema for both groups was one time per night, one treatment course lasting for 15 days; after two courses, the total effective rate,recurrence rate and improvement of intestinal mucosa in both groups were compared. As results,the total effective rate had no statistical differences（96.7%vs 90.0%, P〉0.05）,but later two items of treatment group were significantly superior to control group （98.3% vs 78.3%, 6.7% vs 31.7%, P〈0.05 at all）. Results show that the whole therapeutic effects of two enema are homologous each other,but compound phellodendron solution used in retention enema for treating ulcerative rectitis is more convenient to use, more significant for improving intestinal mucosa and more lower in recurrence rate,thus it is worthy to popularize in clinical application.

关 键 词：溃疡性直肠炎 复方黄柏液 保留灌肠 疗效 

分 类 号：R725.164[医药卫生—儿科]