湖北省部分地区中华按蚊对杀虫剂的抗药性监测  

Monitoring of resistance of Anopheles sinensis to insecticide in partial areas in Hubei Province

作　　者：裴速建[1] 李凯杰[1] 张华勋[1] 胡乐群[1] 黄光全[1] 刘井元[1] 董小蓉[1] 林文[1] 

机构地区：[1]湖北省疾病预防控制中心,湖北武汉430079

出　　处：《中国热带医学》2012年第10期1192-1194,1198,共4页China Tropical Medicine

基　　金：第五轮中国全球基金疟疾项目资助(No.CHN-506-G07-M)

摘　　要：目的了解中华按蚊对溴氰菊酯、氟氯氰菊酯、DDT和马拉硫磷抗药性,为合理使用杀虫剂提供科学依据。方法采用WHO区分剂量标准和方法,观察首只蚊虫击倒时间、击倒率和死亡率,根据校正死亡率判定抗性级别。结果襄州区、广水市、京山县中华按蚊对DDT、溴氰菊酯和氟氯氰菊酯首只蚊虫击倒时间依次为4～42 min、4～20 min和5～18 min,击倒率依次为2.06%～6.60%、4.9%～11.43%和3.23%～23.47%,校正死亡率均小于50%,均为抗性群体;对马拉硫磷首只蚊虫击倒时间10～13 min,击倒率17.76%～35.05%,校正死亡率广水市小于80%为抗性群体、襄州区和京山县在82.6%～88.78%,为初步抗性群体。结论湖北省部分地区中华按蚊对DDT仍具有很高的抗药性,对溴氰菊酯和氟氯氰菊酯也具有很强的抗药性和抗击倒力。应加强监测,现场防制宜适当加大使用剂量,确保防制效果。Objective To understanad the resistance of Anopheles sinensis to deltamethrin, cyfluthrin, DDT and malathi- on. Methods The knockdown time of the first Anopheles, the knockdown rate and the mortality were recorded by WHO dis- crimination dose method and the resistance degree was determined. Results The knockdown time of the first Anophele and the knockdown rate to DDT, deltamethrin and cyfluthrin were 4-42min, 4-20rain and 5-18min,and 2.06-6.60%, 4.9 - 11.43% and 3.23 -23.47% ,the corrected mortality all were less than 50%, the Anopheles were resistance group in the three areas; The knockdown time of the first Anophele ,the knockdown rate to Malathion were 10-13rain and 17.76 - 35.05%, and ,the corrected mortality was less than 80% in Cuangshui city, the Anopheles had were resistance group, the corrected mortality was 82.6-88.78% in Xiangzhou district and Jingshan county, the Anopheles was preliminarily a resistant group. Conclusion The resistance of Anopheles sinensis to DDT was still higher in some areas in Hubei, the resistance and anti-knockdown rate of Anopheles sinensis to cyfluthrin, deltamethrin were also high. Thus the work of monitoring be strengthened and the dose of insec- ticide be increased to maintain effective rushs..

关 键 词：中华按蚊 杀虫剂 抗药性 监测 

分 类 号：R384.1[医药卫生—医学寄生虫学]